EZH2 and E2F6

  • Number of citations of the paper that reports this interaction (PubMedID 15536069)
  • 57
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vivo)

EZH2

E2F6

Description enhancer of zeste 2 polycomb repressive complex 2 subunit E2F transcription factor 6
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronotype ( 30696823)
  • Colorectal or endometrial cancer ( 26621817)
  • Crohn's disease ( 28067908)
  • Familial squamous cell lung carcinoma ( 29924316)
  • Height ( 25282103 31562340)
  • Inflammatory bowel disease ( 28067908)
  • Mean reticulocyte volume ( 32888494)
  • Mean spheric corpuscular volume ( 32888494)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412)
  • Diisocyanate-induced asthma ( 25918132)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Sudden cardiac arrest ( 21658281)
Interacting Genes 77 interacting genes: AKT1 AR ATP1A1 ATP1B1 ATRX BCL11A BRCA1 C7orf25 CCDC85B CDK2 CDK6 CDKN2B-AS1 CEP63 CRY2 DELEC1 DNAJB11 DNMT1 DNMT3A DNMT3B E2F6 EED EHMT1 EPC2 FBXW7 GADD45G GTF3C1 H1-1 H3-4 HDAC1 HOTAIR JAK2 KAT2B KLHDC2 KRTAP10-9 LATS2 LINC00511 MAP3K20 MAP3K7 MAPK8IP2 MAPKAPK3 MED1 MELK MUC1 MYCN NINL PFDN1 PHB2 PHF1 PIN4 PJA1 POLA2 PRDM14 PRMT5 PSMB6 RASA1 RBL2 RELA RELB RIN3 RPN2 RPS6KA5 SIRT1 SMN1 SMS SMYD3 SUV39H1 SUZ12 TAF1D TK1 TNFSF11 TRIM55 TRIM63 USP1 VAV1 WDR61 WSB2 ZMYND11 29 interacting genes: APP ARAF BMI1 BRDT CENPU DNMT1 DNMT3L DNTTIP1 DRD2 E2F1 EPC1 EZH1 EZH2 HMG20B INO80B KRTAP10-7 MDN1 NFYA PCGF6 PIK3R3 RING1 RYBP SMARCA4 TFDP1 TFDP2 ZBTB17 ZBTB32 ZFPM2 ZMYND11
Entrez ID 2146 1876
HPRD ID 03342 04251
Ensembl ID ENSG00000106462 ENSG00000169016
Uniprot IDs A0A090N8E9 Q15910 S4S3R8 A0A0S2Z3K8 O75461 Q53YM3 Q6Q9Z5
PDB IDs 2C6V 4MI0 4MI5 5GSA 5H14 5H15 5H17 5H19 5H24 5H25 5HYN 5IJ7 5IJ8 5LS6 5U5T 5U62 5WG6 5WUK 6C23 6C24 6P5L 6U4Y 6WKR 7AT8
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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