ALCAM and PIK3CA

ALCAM

PIK3CA

Description activated leukocyte cell adhesion molecule phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Age-related cognitive decline (memory) (slope of z-scores) ( 30954325)
  • Alzheimer's disease ( 33074286)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Apolipoprotein A1 levels ( 32203549)
  • Blood protein levels ( 30072576 29875488)
  • Body mass index ( 25673413)
  • Breast cancer ( 31757997)
  • Chronotype ( 30696823)
  • Cortical surface area ( 32963231)
  • Cortical surface area (visual PC2) ( 32198502)
  • Cortical volume ( 32963231)
  • Erectile dysfunction in type 1 diabetes ( 22704111)
  • Glaucoma (primary open-angle) ( 33627673)
  • Glomerular filtration rate in chronic kidney disease ( 26420894)
  • HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • Initial pursuit acceleration ( 29064472)
  • Intraocular pressure ( 29617998)
  • Irritable mood ( 29500382)
  • Metabolite levels ( 23823483)
  • Ovarian disease with few adhesions ( 28333195)
  • Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311)
  • Visceral fat ( 30942860)
Interacting Genes 6 interacting genes: ART3 ATE1 CD6 EGFR LAG3 PIK3CA 78 interacting genes: ACOT8 ADAP1 AKT1 ALCAM AMBP APLP2 APPL1 ARAF ATP5IF1 ATR BEX1 BEX2 CCND2 CRIP1 CSF1R CYTH2 CYTH3 DDX5 DNAJB6 EGFR FANCC FASLG FBP2 FTL GABRB1 GALNT12 GLIS2 GNAQ GRIN2B HRAS IL13RA2 IL24 IL3 IRS2 IRS4 ITIH1 KRAS LCK LYPLA1 MAP2K1 MAP3K9 MRAS MYC NEDD4L NEDD9 NRAS PDGFRA PDGFRB PDK1 PIK3R1 PIK3R3 PRKCD PRKCI PSMC3IP PTPN11 RASD2 RASGRP3 RELA RHOC RPS20 RPS6KB1 SFRP4 SGK1 SH3KBP1 SMAD2 SMAD3 SNX9 SQSTM1 STAT1 STK11 THRSP TICAM1 TMOD1 TNFSF13 TRA2B UFD1 UMPS VARS2
Entrez ID 214 5290
HPRD ID 03389 01382
Ensembl ID ENSG00000170017 ENSG00000121879
Uniprot IDs B3KNN9 Q13740 P42336 Q4LE51
PDB IDs 1KJC 5A2F 2ENQ 2RD0 3HHM 3HIZ 3ZIM 4JPS 4L1B 4L23 4L2Y 4OVU 4OVV 4TUU 4TV3 4WAF 4YKN 4ZOP 5DXH 5DXT 5FI4 5ITD 5SW8 5SWG 5SWO 5SWP 5SWR 5SWT 5SX8 5SX9 5SXA 5SXB 5SXC 5SXD 5SXE 5SXF 5SXI 5SXJ 5SXK 5UBR 5UK8 5UKJ 5UL1 5XGH 5XGI 5XGJ 6GVF 6GVG 6GVH 6GVI 6NCT 6OAC 6PYS 6VO7 7K6M 7K6N 7K6O 7K71
Enriched GO Terms of Interacting Partners?
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