EXTL1 and SDR16C5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		EXTL1	SDR16C5
Description		exostosin like glycosyltransferase 1	short chain dehydrogenase/reductase family 16C member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane	Chromatin Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Plasma Membrane Integral Component Of Membrane Transcription Repressor Complex
	Molecular Function	Protein Binding Acetylglucosaminyltransferase Activity Glucuronosyltransferase Activity Glycosyltransferase Activity Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase Activity	Transcription Corepressor Activity NAD-retinol Dehydrogenase Activity Protein Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Binding
	Biological Process	Skeletal System Development Protein Glycosylation	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Deacetylation Negative Regulation Of Histone Acetylation Retinol Metabolic Process Retinal Metabolic Process Keratinocyte Proliferation
Pathways		XBP1(S) activates chaperone genes	RA biosynthesis pathway
Drugs
Diseases
GWAS			Depressive symptoms x dependent stressful life events interaction (2df test) ( 30718454) Height ( 28552196 20881960 31562340) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: CLDN9 DISC1 ERGIC3 FNDC9 SDR16C5 TMEM14B TMEM237	12 interacting genes: EHHADH EXTL1 FUNDC2 GAD2 HSFX1 HSFX2 NDRG4 NLK SENP2 SNX1 SYT16 TTPA
Entrez ID		2134	195814
HPRD ID		03441	12351
Ensembl ID		ENSG00000158008	ENSG00000170786
Uniprot IDs		Q92935	B3KT84 G3V145 Q8N3Y7
PDB IDs
Enriched GO Terms of Interacting Partners?
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