SDR16C5 and HSFX1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SDR16C5	HSFX1
Description		short chain dehydrogenase/reductase family 16C member 5	heat shock transcription factor family, X-linked 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Plasma Membrane Integral Component Of Membrane Transcription Repressor Complex	Chromatin Nucleus Cytoplasm
	Molecular Function	Transcription Corepressor Activity NAD-retinol Dehydrogenase Activity Protein Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Deacetylation Negative Regulation Of Histone Acetylation Retinol Metabolic Process Retinal Metabolic Process Keratinocyte Proliferation	Regulation Of Transcription By RNA Polymerase II
Pathways		RA biosynthesis pathway
Drugs
Diseases
GWAS		Depressive symptoms x dependent stressful life events interaction (2df test) ( 30718454) Height ( 28552196 20881960 31562340) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278)
Interacting Genes		12 interacting genes: EHHADH EXTL1 FUNDC2 GAD2 HSFX1 HSFX2 NDRG4 NLK SENP2 SNX1 SYT16 TTPA	11 interacting genes: AGTRAP ATXN1 ATXN1L CACFD1 KRTAP12-2 MAL2 MICOS13 MTIF3 RBFOX1 SDR16C5 SYP
Entrez ID		195814	100506164
HPRD ID		12351
Ensembl ID		ENSG00000170786	ENSG00000171116
Uniprot IDs		B3KT84 G3V145 Q8N3Y7	A0A140VK21 Q9UBD0
PDB IDs
Enriched GO Terms of Interacting Partners?
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