SDR16C5 and EXTL1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SDR16C5	EXTL1
Description		short chain dehydrogenase/reductase family 16C member 5	exostosin like glycosyltransferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Plasma Membrane Integral Component Of Membrane Transcription Repressor Complex	Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Transcription Corepressor Activity NAD-retinol Dehydrogenase Activity Protein Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Binding	Protein Binding Acetylglucosaminyltransferase Activity Glucuronosyltransferase Activity Glycosyltransferase Activity Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Deacetylation Negative Regulation Of Histone Acetylation Retinol Metabolic Process Retinal Metabolic Process Keratinocyte Proliferation	Skeletal System Development Protein Glycosylation
Pathways		RA biosynthesis pathway	XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Depressive symptoms x dependent stressful life events interaction (2df test) ( 30718454) Height ( 28552196 20881960 31562340) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278)
Interacting Genes		12 interacting genes: EHHADH EXTL1 FUNDC2 GAD2 HSFX1 HSFX2 NDRG4 NLK SENP2 SNX1 SYT16 TTPA	7 interacting genes: CLDN9 DISC1 ERGIC3 FNDC9 SDR16C5 TMEM14B TMEM237
Entrez ID		195814	2134
HPRD ID		12351	03441
Ensembl ID		ENSG00000170786	ENSG00000158008
Uniprot IDs		B3KT84 G3V145 Q8N3Y7	Q92935
PDB IDs
Enriched GO Terms of Interacting Partners?
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