SPNS3 and BTN2A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SPNS3	BTN2A2
Description		sphingolipid transporter 3 (putative)	butyrophilin subfamily 2 member A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Transmembrane Transporter Activity	Signaling Receptor Binding Protein Binding
	Biological Process	Lipid Transport Transmembrane Transport	Regulation Of Cytokine Production Negative Regulation Of Cytokine Production Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Activated T Cell Proliferation T Cell Receptor Signaling Pathway
Pathways			Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Coronary artery disease in type 1 diabetes ( 29695241) Obesity-related traits ( 23251661) Small cell lung carcinoma ( 28604730)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) General cognitive ability ( 29844566) Headache ( 29397368) Hip circumference adjusted for BMI ( 34021172) Intelligence (MTAG) ( 29326435) Liver iron content ( 34128465) Neurociticism ( 29500382) Refractive error ( 32231278) Schizophrenia ( 19571809) Smoking initiation ( 33082346) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		8 interacting genes: BTN2A2 FXYD3 LRRC25 PLP1 STATH STRIT1 SYNGR1 TMEM60	42 interacting genes: AQP6 BIK CD53 CD79A CISD2 CREB3 EBP ELOVL4 EMP1 ERGIC3 EVI2B FAM209A FATE1 FFAR2 GJB3 GPR42 GPRC5D GPX8 HSD3B7 KIR2DL3 LHFPL5 LMNA MRM3 MUC1 PEX12 PSMA3 SEC11C SLC10A6 SLC14A1 SLC16A2 SLC1A3 SLC30A4 SLC39A2 SPNS3 STX1A SYT1 TMEM14B TMEM179B TMEM237 TMEM31 TMEM52B TMX2
Entrez ID		201305	10385
HPRD ID		14531	12545
Ensembl ID		ENSG00000182557	ENSG00000124508
Uniprot IDs		Q6ZMD2	A0A024R038 Q8WVV5
PDB IDs
Enriched GO Terms of Interacting Partners?
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