BTN2A2 and CISD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BTN2A2	CISD2
Description		butyrophilin subfamily 2 member A2	CDGSH iron sulfur domain 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Protein-containing Complex Perinuclear Endoplasmic Reticulum
	Molecular Function	Signaling Receptor Binding Protein Binding	RNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Regulation Of Cytokine Production Negative Regulation Of Cytokine Production Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Activated T Cell Proliferation T Cell Receptor Signaling Pathway	Autophagy Of Mitochondrion Multicellular Organism Aging Regulation Of Autophagy
Pathways		Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) General cognitive ability ( 29844566) Headache ( 29397368) Hip circumference adjusted for BMI ( 34021172) Intelligence (MTAG) ( 29326435) Liver iron content ( 34128465) Neurociticism ( 29500382) Refractive error ( 32231278) Schizophrenia ( 19571809) Smoking initiation ( 33082346) Subcortical volume (MOSTest) ( 32665545)	Asthma and attention deficit hyperactivity disorder ( 31619474) Estimated glomerular filtration rate ( 31152163) Primary biliary cholangitis ( 26394269) Schizophrenia ( 28991256) Type 2 diabetes ( 28869590)
Interacting Genes		42 interacting genes: AQP6 BIK CD53 CD79A CISD2 CREB3 EBP ELOVL4 EMP1 ERGIC3 EVI2B FAM209A FATE1 FFAR2 GJB3 GPR42 GPRC5D GPX8 HSD3B7 KIR2DL3 LHFPL5 LMNA MRM3 MUC1 PEX12 PSMA3 SEC11C SLC10A6 SLC14A1 SLC16A2 SLC1A3 SLC30A4 SLC39A2 SPNS3 STX1A SYT1 TMEM14B TMEM179B TMEM237 TMEM31 TMEM52B TMX2	58 interacting genes: AIG1 APOL2 APP AQP10 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C2CD2L C4orf3 CDIPT CFHR5 CLDN10 CLN6 CYBC1 EHHADH EMD FAM241B GALNT15 GAST GPR37L1 HHATL IER3 KIR2DL3 LEPROTL1 LRP10 MAN2B2 MIP NAPB NRG4 NSG1 PGAP2 PLPP4 PLPPR2 PNKP POMGNT1 RTP2 RUSF1 SEC22A SERP2 SLC13A3 SLC35B4 SMIM1 SNORC SPP1 STX12 STX7 THSD7B TMEM187 TMEM243 TMEM43 TMEM86A TSPAN33 TTPA VAMP4 VKORC1L1 YIPF6
Entrez ID		10385	493856
HPRD ID		12545	17413
Ensembl ID		ENSG00000124508	ENSG00000145354
Uniprot IDs		A0A024R038 Q8WVV5	Q8N5K1
PDB IDs			3FNV 4OO7 4OOA
Enriched GO Terms of Interacting Partners?
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