PKD1 and PXN

  • Number of citations of the paper that reports this interaction (PubMedID 11113628)
  • 37
  • Data Source:
  • HPRD (in vivo, in vitro)

PKD1

PXN

Description polycystin 1, transient receptor potential channel interacting paxillin
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Appendicular lean mass ( 33097823)
  • Dilated cardiomyopathy ( 33677556)
  • Estimated glomerular filtration rate ( 31451708)
  • Estimated glomerular filtration rate in non-diabetics ( 31451708)
  • Heel bone mineral density ( 30598549)
  • Height ( 28552196)
  • High light scatter reticulocyte count ( 32888494)
  • Hypertrophic cardiomyopathy (MTAG) ( 33495596)
  • Low hand grip strength (60 years and older) (EWGSOP) ( 33510174)
  • Major depressive disorder ( 29317602)
  • Neutrophil count ( 32888494)
  • Systolic blood pressure ( 30578418)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Bipolar disorder ( 31043756)
  • Left ventricle wall thickness ( 33495596)
  • Left ventricular end-systolic volume ( 33495596)
  • Left ventricular mass to end-diastolic volume ratio ( 33495596)
  • Mean spheric corpuscular volume ( 32888494)
  • Platelet count ( 29403010)
Interacting Genes 39 interacting genes: ACTN1 ATF7IP BCAR1 CDH1 COL1A1 COL2A1 CTNNA1 CTNNB1 DDX58 DES FN1 HDAC9 JAK2 JUP KRT18 KRT8 LTB4R2 MARK2 NADSYN1 NCF1 NCK2 NTHL1 NTN3 OR1F1 PDPK1 PIP5K1C PKD2 PPL PTK2 PTPRG PXN RGS7 RPL3L SIAH1 SOX17 SRC TLN1 VCL VIM 90 interacting genes: ABL1 ACO1 AHCY AR ARHGEF7 ASAP1 ASAP2 BCAR1 BCL2 BLK CASP3 CEACAM1 CLTC CREB3L2 CRK CRKL CSK DGUOK DPY30 EPHB1 FYN GART GIT1 GIT2 GRB2 GSK3A GSK3B GSN HDAC6 ILK IMPDH2 ITGA4 ITGA6 ITGA9 ITGAV ITGB1 ITGB3 LCK LIMK1 LMO1 LMO3 MAPK1 MAPK3 MAPK8 MATK NCK1 NEDD9 NF2 PABPC1 PAK1 PAK3 PARVA PCM1 PDPK1 PKD1 PLEKHH2 PLEKHN1 POLR1D PPP2CA PPP2R5C PTEN PTK2 PTK2B PTPN11 PTPN12 PTPRH RASA1 REPS2 RHOU RNF5 SCARB1 SDC4 SELE SH3RF1 SORBS1 SRC SYK TCEANC TGM2 TLN1 TRIM15 TRIP6 TUBA1B TUBA3C TUBA8 TUBG1 TUBG2 VCL WHRN YES1
Entrez ID 5310 5829
HPRD ID 03203 03937
Ensembl ID ENSG00000008710 ENSG00000089159
Uniprot IDs P98161 A0A140VJQ8 P49023
PDB IDs 1B4R 6A70 1KKY 1KL0 1OW6 1OW7 1OW8 2K2R 2O9V 2VZD 2VZG 2VZI 3GM1 3PY7 3RQE 3RQF 3RQG 3U3F 4EDN 4R32 4XGZ 4XH2 5UWH 6IUI 6PW8 6U4M 6U4N
Enriched GO Terms of Interacting Partners?
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