DYNC1I1 and DDX19B

		DYNC1I1	DDX19B
Description		dynein cytoplasmic 1 intermediate chain 1	DEAD-box helicase 19B
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Spindle Pole Nucleus Cytoplasm Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm Recycling Endosome	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytoplasmic Stress Granule Membrane Extracellular Exosome
	Molecular Function	Cytoskeletal Motor Activity Microtubule Motor Activity Protein Binding Microtubule Binding Spectrin Binding Dynein Light Chain Binding Dynein Heavy Chain Binding	RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity
	Biological Process	Microtubule-based Movement Transport Along Microtubule Vesicle Transport Along Microtubule	MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 28552196) Immune reponse to smallpox (secreted IL-10) ( 22610502) Knee osteoarthritis ( 27696742) Multisite chronic pain ( 33830993 31194737) Obesity-related traits ( 23251661) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Refractive error ( 32231278)	Apolipoprotein B levels ( 32203549) Brain morphology (MOSTest) ( 32665545) Malaria ( 31844061) Pursuit maintenance gain ( 29064472) Systolic blood pressure ( 30578418)
Interacting Genes		39 interacting genes: ANXA7 BICD1 CADM4 CDKN1A DDX19B DNM2 DYNLL1 DYNLL2 DYNLRB1 DYNLT1 DYNLT3 EMILIN1 FAM110A FAM83D FBP1 GRB7 GSK3B KAT7 KLC2 MCC MCM7 NAGK NDUFV2 NPTX2 NUDT21 NUP214 PIN1 RAP1GAP RCC1 RUNDC3B SEM1 SERPINE1 SMN1 STAU1 TAOK1 TK1 TRIM58 WDCP ZKSCAN1	16 interacting genes: APP B3GALT4 DCK DYNC1I1 IKBKG MIF4GD NUP214 PLA2G15 POT1 PRPSAP1 RACK1 RWDD2B SKP1 TERF1 UBC XPO7
Entrez ID		1780	11269
HPRD ID		04798	05781
Ensembl ID		ENSG00000158560	ENSG00000157349
Uniprot IDs		A4D1I7 O14576 Q8N542	A0A024QZ90 A0A0U4B4U6 B4DL69 Q9UMR2
PDB IDs			3EWS 3FHC 3FHT 3FMO 3FMP 3G0H 6B4I 6B4J 6B4K
Enriched GO Terms of Interacting Partners?
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