DYNC1I1 and DYNLT3

Number of citations of the paper that reports this interaction (PubMedID 28718761)
39

Data Source:
BioGRID (proximity labelling technology, two hybrid)

		DYNC1I1	DYNLT3
Description		dynein cytoplasmic 1 intermediate chain 1	dynein light chain Tctex-type 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Spindle Pole Nucleus Cytoplasm Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm Recycling Endosome	Kinetochore Nucleus Cytoplasm Cytoplasmic Dynein Complex Mitotic Spindle Astral Microtubule
	Molecular Function	Cytoskeletal Motor Activity Microtubule Motor Activity Protein Binding Microtubule Binding Spectrin Binding Dynein Light Chain Binding Dynein Heavy Chain Binding	Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding
	Biological Process	Microtubule-based Movement Transport Along Microtubule Vesicle Transport Along Microtubule	Microtubule-based Movement Cell Cycle Regulation Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Cell Division
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 28552196) Immune reponse to smallpox (secreted IL-10) ( 22610502) Knee osteoarthritis ( 27696742) Multisite chronic pain ( 33830993 31194737) Obesity-related traits ( 23251661) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Refractive error ( 32231278)
Interacting Genes		39 interacting genes: ANXA7 BICD1 CADM4 CDKN1A DDX19B DNM2 DYNLL1 DYNLL2 DYNLRB1 DYNLT1 DYNLT3 EMILIN1 FAM110A FAM83D FBP1 GRB7 GSK3B KAT7 KLC2 MCC MCM7 NAGK NDUFV2 NPTX2 NUDT21 NUP214 PIN1 RAP1GAP RCC1 RUNDC3B SEM1 SERPINE1 SMN1 STAU1 TAOK1 TK1 TRIM58 WDCP ZKSCAN1	16 interacting genes: C2orf15 CCL28 CD5 CYBB DYNC1I1 DYNC1I2 DYNLT1 FOS IFITM1 NIF3L1 PMS1 PVR TESC UIMC1 VDAC1 ZC3H14
Entrez ID		1780	6990
HPRD ID		04798	02249
Ensembl ID		ENSG00000158560	ENSG00000165169
Uniprot IDs		A4D1I7 O14576 Q8N542	P51808
PDB IDs
Enriched GO Terms of Interacting Partners?
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