DDX19B and DYNC1I1

		DDX19B	DYNC1I1
Description		DEAD-box helicase 19B	dynein cytoplasmic 1 intermediate chain 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytoplasmic Stress Granule Membrane Extracellular Exosome	Kinetochore Spindle Pole Nucleus Cytoplasm Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity	Cytoskeletal Motor Activity Microtubule Motor Activity Protein Binding Microtubule Binding Spectrin Binding Dynein Light Chain Binding Dynein Heavy Chain Binding
	Biological Process	MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus	Microtubule-based Movement Transport Along Microtubule Vesicle Transport Along Microtubule
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Brain morphology (MOSTest) ( 32665545) Malaria ( 31844061) Pursuit maintenance gain ( 29064472) Systolic blood pressure ( 30578418)	Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 28552196) Immune reponse to smallpox (secreted IL-10) ( 22610502) Knee osteoarthritis ( 27696742) Multisite chronic pain ( 33830993 31194737) Obesity-related traits ( 23251661) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Refractive error ( 32231278)
Interacting Genes		16 interacting genes: APP B3GALT4 DCK DYNC1I1 IKBKG MIF4GD NUP214 PLA2G15 POT1 PRPSAP1 RACK1 RWDD2B SKP1 TERF1 UBC XPO7	39 interacting genes: ANXA7 BICD1 CADM4 CDKN1A DDX19B DNM2 DYNLL1 DYNLL2 DYNLRB1 DYNLT1 DYNLT3 EMILIN1 FAM110A FAM83D FBP1 GRB7 GSK3B KAT7 KLC2 MCC MCM7 NAGK NDUFV2 NPTX2 NUDT21 NUP214 PIN1 RAP1GAP RCC1 RUNDC3B SEM1 SERPINE1 SMN1 STAU1 TAOK1 TK1 TRIM58 WDCP ZKSCAN1
Entrez ID		11269	1780
HPRD ID		05781	04798
Ensembl ID		ENSG00000157349	ENSG00000158560
Uniprot IDs		A0A024QZ90 A0A0U4B4U6 B4DL69 Q9UMR2	A4D1I7 O14576 Q8N542
PDB IDs		3EWS 3FHC 3FHT 3FMO 3FMP 3G0H 6B4I 6B4J 6B4K
Enriched GO Terms of Interacting Partners?
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