DLG4 and KCNJ2

  • Number of citations of the paper that reports this interaction (PubMedID 10627592)
  • 37
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)
  • HPRD (two hybrid, in vivo)

DLG4

KCNJ2

Description discs large MAGUK scaffold protein 4 potassium inwardly rectifying channel subfamily J member 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adolescent idiopathic scoliosis (severe) ( 24023777)
  • Alanine aminotransferase levels ( 33547301)
  • Aspartate aminotransferase levels ( 33547301)
  • Atrial fibrillation ( 29892015)
  • Birth weight ( 31043758)
  • Chin dimples ( 27182965)
  • Dentures ( 31235808)
  • Depressive episodes in bipolar disorder ( 26297903)
  • Early cardiac repolarization ( 22342860)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Electrocardiographic traits (multivariate) ( 32602732)
  • Formal thought disorder in schizophrenia ( 22648509)
  • HDL cholesterol levels ( 32203549 32109663)
  • Hip circumference adjusted for BMI ( 25673412)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Lung function (forced vital capacity) ( 24929828)
  • Macular thickness ( 30535121)
  • Metabolite levels ( 23823483)
  • Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
  • Obesity-related traits ( 23251661)
  • Primary tooth development (number of teeth) ( 23704328 20195514)
  • Primary tooth development (time to first tooth eruption) ( 23704328 20195514)
  • Prudent dietary pattern ( 28644415)
  • Pulmonary function (smoking interaction) ( 23284291)
  • QT interval ( 30679814 24952745 19305409 29874175)
  • Refractive error ( 23396134)
  • Renal overload gout ( 32238385)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Spherical equivalent (joint analysis main effects and education interaction) ( 27020472)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • T wave morphology restitution during exercise ( 31607149)
  • T wave morphology restitution during exercise (MTAG) ( 31607149)
  • Thyrotoxic hypokalemic periodic paralysis ( 22863731 22399142)
  • Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781)
  • Thyrotoxic periodic paralysis ( 33105104)
  • TPE interval (response to exercise) ( 32386560)
  • TPE interval (resting) ( 32386560)
  • Triglyceride levels ( 32203549)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
  • White matter hyperintensity volume ( 33293549)
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
Interacting Genes 135 interacting genes: ABHD17A ACTN2 ADGRB1 ADGRB2 ADGRL1 ADRB1 AKAP5 ARHGAP32 ARRB2 ASIC3 ATP2B2 ATP2B4 BEGAIN CACNG2 CASK CD46 CIT CLU CNKSR2 CRHR1 CRIPT CYLD DLG2 DLG3 DLGAP1 DLGAP2 DLGAP3 DLGAP4 DRD1 DYNLL1 EEF1G EFNB2 ERBB2 ERBB4 ERBIN EXOC4 FTH1 FYN FZD1 FZD2 FZD4 FZD7 GDA GLS2 GNG13 GOLGA2 GPSM2 GRIK1 GRIK2 GRIK5 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRIN3A GRIN3B GUCY1A2 HGS HNRNPC HTR2A HTR2C HTT IL13RA1 KCNA1 KCNA2 KCNA3 KCNA4 KCNA5 KCND2 KCNJ10 KCNJ12 KCNJ2 KCNJ4 KHDRBS1 KIF13B KIF1B LIN7A LIN7B LRFN1 LRP1 LRP2 LRP8 LRRC1 LYN LZTS2 MAP1A MAP3K10 MAPK12 MDM2 MPND MPP1 MT-CO1 NCKIPSD NDOR1 NLGN1 NLGN2 NLGN3 NLGN4X NOMO1 NOS1 PCDH10 PCMT1 PEX19 PICK1 PRKCA PRR16 PTK2B PTPRG RALBP1 RASSF4 RPS6KA1 SCN5A SEMA4B SEMA4C SEMA4F SEMA4G SHANK1 SHANK2 SIPA1L1 SLC4A7 SPRR2A SRC SYNGAP1 TAMALIN TANC1 THOC3 TJAP1 TRAF6 TUBB2B VMAC WDR74 WNT3A YES1 ZDHHC17 21 interacting genes: AKAP5 ARL13B CASK DLG1 DLG2 DLG3 DLG4 FLNA IL16 KCNJ11 KCNJ15 KCNJ16 KCNJ18 KCNJ4 KCNJ8 PATJ SDC3 SDCBP SEC22A TRAK2 UTP18
Entrez ID 1742 3759
HPRD ID 04199 02815
Ensembl ID ENSG00000132535 ENSG00000123700
Uniprot IDs B7Z4H2 B7Z647 B9EGL1 P78352 P63252
PDB IDs 1KEF 2MES 3I4W 3K82 3ZRT 5J7J 5JXB 6QJD 6QJF 6QJG 6QJI 6QJJ 6QJK 6QJL 6QJN 6SPV 6SPZ 6SPZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?