KCNJ2 and CASK

  • Number of citations of the paper that reports this interaction (PubMedID 15024025)
  • 68
  • Data Source:
  • HPRD (in vitro)

KCNJ2

CASK

Description potassium inwardly rectifying channel subfamily J member 2 calcium/calmodulin dependent serine protein kinase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adolescent idiopathic scoliosis (severe) ( 24023777)
  • Alanine aminotransferase levels ( 33547301)
  • Aspartate aminotransferase levels ( 33547301)
  • Atrial fibrillation ( 29892015)
  • Birth weight ( 31043758)
  • Chin dimples ( 27182965)
  • Dentures ( 31235808)
  • Depressive episodes in bipolar disorder ( 26297903)
  • Early cardiac repolarization ( 22342860)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Electrocardiographic traits (multivariate) ( 32602732)
  • Formal thought disorder in schizophrenia ( 22648509)
  • HDL cholesterol levels ( 32203549 32109663)
  • Hip circumference adjusted for BMI ( 25673412)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Lung function (forced vital capacity) ( 24929828)
  • Macular thickness ( 30535121)
  • Metabolite levels ( 23823483)
  • Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
  • Obesity-related traits ( 23251661)
  • Primary tooth development (number of teeth) ( 23704328 20195514)
  • Primary tooth development (time to first tooth eruption) ( 23704328 20195514)
  • Prudent dietary pattern ( 28644415)
  • Pulmonary function (smoking interaction) ( 23284291)
  • QT interval ( 30679814 24952745 19305409 29874175)
  • Refractive error ( 23396134)
  • Renal overload gout ( 32238385)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Spherical equivalent (joint analysis main effects and education interaction) ( 27020472)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • T wave morphology restitution during exercise ( 31607149)
  • T wave morphology restitution during exercise (MTAG) ( 31607149)
  • Thyrotoxic hypokalemic periodic paralysis ( 22863731 22399142)
  • Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781)
  • Thyrotoxic periodic paralysis ( 33105104)
  • TPE interval (response to exercise) ( 32386560)
  • TPE interval (resting) ( 32386560)
  • Triglyceride levels ( 32203549)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
  • White matter hyperintensity volume ( 33293549)
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
Interacting Genes 21 interacting genes: AKAP5 ARL13B CASK DLG1 DLG2 DLG3 DLG4 FLNA IL16 KCNJ11 KCNJ15 KCNJ16 KCNJ18 KCNJ4 KCNJ8 PATJ SDC3 SDCBP SEC22A TRAK2 UTP18 87 interacting genes: AKAP9 APBA1 ATP2B4 BNIP3L C20orf85 CADM1 CASKIN1 CDK9 CNTNAP2 CNTNAP4 DDX54 DLG1 DLG4 DUSP3 ELL2 EPB41 EPS8 ERBIN F11R FCHSD2 FMR1 GCNT3 GLS2 GRIK2 GRIN2A GTSE1 HGS ID1 IL15RA IL18 KCNA4 KCNJ12 KCNJ2 KCNJ4 KIF2A KLC4 LIN7A LIN7B MAPRE1 MAPRE2 MARK2 MARS1 MED1 MLLT6 MLX NDEL1 NPHS1 NRXN1 NRXN2 NRXN3 NTN4 P2RX7 PARD3B PARD6G PCBP2 PCM1 PKP2 PLK2 PPP4R3A PRC1 PRKCI PRKD2 PRKN PRPF3 PTGS2 RAB3A RBBP6 RBM10 RBM14 RBM5 RPA2 RPH3A SDC1 SDC2 SDC3 SDC4 SF3B2 SH2D4A SLAIN2 SRPK2 TANC1 TBR1 TRIM22 TSPYL2 WHRN WNT7B YWHAE
Entrez ID 3759 8573
HPRD ID 02815 02164
Ensembl ID ENSG00000123700 ENSG00000147044
Uniprot IDs P63252 A0A2R8Y6F8 A0A2R8YE77 A0A7I2RJN6 O14936
PDB IDs 6SPZ 1KGD 1KWA 1ZL8 3C0G 3C0H 3C0I 3MFR 3MFS 3MFT 3MFU 3TAC 6KMH
Enriched GO Terms of Interacting Partners?
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