KCNJ2 and FLNA

  • Number of citations of the paper that reports this interaction (PubMedID 12923176)
  • 37
  • Data Source:
  • HPRD (two hybrid, in vitro)

KCNJ2

FLNA

Description potassium inwardly rectifying channel subfamily J member 2 filamin A
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adolescent idiopathic scoliosis (severe) ( 24023777)
  • Alanine aminotransferase levels ( 33547301)
  • Aspartate aminotransferase levels ( 33547301)
  • Atrial fibrillation ( 29892015)
  • Birth weight ( 31043758)
  • Chin dimples ( 27182965)
  • Dentures ( 31235808)
  • Depressive episodes in bipolar disorder ( 26297903)
  • Early cardiac repolarization ( 22342860)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Electrocardiographic traits (multivariate) ( 32602732)
  • Formal thought disorder in schizophrenia ( 22648509)
  • HDL cholesterol levels ( 32203549 32109663)
  • Hip circumference adjusted for BMI ( 25673412)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Lung function (forced vital capacity) ( 24929828)
  • Macular thickness ( 30535121)
  • Metabolite levels ( 23823483)
  • Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
  • Obesity-related traits ( 23251661)
  • Primary tooth development (number of teeth) ( 23704328 20195514)
  • Primary tooth development (time to first tooth eruption) ( 23704328 20195514)
  • Prudent dietary pattern ( 28644415)
  • Pulmonary function (smoking interaction) ( 23284291)
  • QT interval ( 30679814 24952745 19305409 29874175)
  • Refractive error ( 23396134)
  • Renal overload gout ( 32238385)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Spherical equivalent (joint analysis main effects and education interaction) ( 27020472)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • T wave morphology restitution during exercise ( 31607149)
  • T wave morphology restitution during exercise (MTAG) ( 31607149)
  • Thyrotoxic hypokalemic periodic paralysis ( 22863731 22399142)
  • Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781)
  • Thyrotoxic periodic paralysis ( 33105104)
  • TPE interval (response to exercise) ( 32386560)
  • TPE interval (resting) ( 32386560)
  • Triglyceride levels ( 32203549)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
  • White matter hyperintensity volume ( 33293549)
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
  • Immature fraction of reticulocytes ( 32888494)
  • White blood cell count ( 32888494)
Interacting Genes 21 interacting genes: AKAP5 ARL13B CASK DLG1 DLG2 DLG3 DLG4 FLNA IL16 KCNJ11 KCNJ15 KCNJ16 KCNJ18 KCNJ4 KCNJ8 PATJ SDC3 SDCBP SEC22A TRAK2 UTP18 100 interacting genes: ADAMTSL4 APC AR ARHGAP24 ARRB1 ARRB2 ASB2 BRCA1 BRCA2 CALCR CAMK2G CASR CAV1 CCNB1 CDC42 CEACAM1 CMIP DCN DDIT4L DRD1 DRD2 DRD3 DUX4 ERBB3 F3 FABP1 FBLIM1 FILIP1 FLNB FURIN GP1BA GRIK1 GRIK3 GRM4 GRM5 GRM7 GRM8 HHLA3 HMGB2 HNRNPD HSPA6 HSPB7 ITGB1 ITGB3 ITGB5 ITGB6 ITGB7 KCNE4 KCNJ2 KLHL12 LGALS14 LMNA MAP2K4 MAPK14 MCPH1 MTDH MTNR1A MTNR1B MYOT MYOZ1 NLGN3 NPHP1 OPRM1 PAK1 PCBP2 PELO PHOSPHO2 PLEKHF2 PRKCA PSEN1 PSEN2 PTEN RAC1 RALA REL RFLNA RHOA SELE SH2B3 SHBG SIGLEC10 SIRPA SMAD3 SMAD5 SPANXD SRC SUMO2 SVIL SYNPO2 TCF4 TLR10 TNIP2 TP73 TRAF2 TRIM55 TRIO TTN USP19 VHL YWHAG
Entrez ID 3759 2316
HPRD ID 02815 02060
Ensembl ID ENSG00000123700 ENSG00000196924
Uniprot IDs P63252 P21333 Q60FE5 Q6NXF2
PDB IDs 6SPZ 2AAV 2BP3 2BRQ 2J3S 2JF1 2K3T 2K7P 2K7Q 2MTP 2W0P 2WFN 3CNK 3HOC 3HOP 3HOR 3ISW 3RGH 4M9P 4P3W 5XR1 6D8C 6EW1
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?