DLG1 and KCNJ2

  • Number of citations of the paper that reports this interaction (PubMedID 11181181)
  • 39
  • Data Source:
  • BioGRID (pull down)
  • HPRD (in vivo, in vitro)

DLG1

KCNJ2

Description discs large MAGUK scaffold protein 1 potassium inwardly rectifying channel subfamily J member 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adolescent idiopathic scoliosis (severe) ( 24023777)
  • Alanine aminotransferase levels ( 33547301)
  • Aspartate aminotransferase levels ( 33547301)
  • Atrial fibrillation ( 29892015)
  • Birth weight ( 31043758)
  • Chin dimples ( 27182965)
  • Dentures ( 31235808)
  • Depressive episodes in bipolar disorder ( 26297903)
  • Early cardiac repolarization ( 22342860)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Electrocardiographic traits (multivariate) ( 32602732)
  • Formal thought disorder in schizophrenia ( 22648509)
  • HDL cholesterol levels ( 32203549 32109663)
  • Hip circumference adjusted for BMI ( 25673412)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Lung function (forced vital capacity) ( 24929828)
  • Macular thickness ( 30535121)
  • Metabolite levels ( 23823483)
  • Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
  • Obesity-related traits ( 23251661)
  • Primary tooth development (number of teeth) ( 23704328 20195514)
  • Primary tooth development (time to first tooth eruption) ( 23704328 20195514)
  • Prudent dietary pattern ( 28644415)
  • Pulmonary function (smoking interaction) ( 23284291)
  • QT interval ( 30679814 24952745 19305409 29874175)
  • Refractive error ( 23396134)
  • Renal overload gout ( 32238385)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Spherical equivalent (joint analysis main effects and education interaction) ( 27020472)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • T wave morphology restitution during exercise ( 31607149)
  • T wave morphology restitution during exercise (MTAG) ( 31607149)
  • Thyrotoxic hypokalemic periodic paralysis ( 22863731 22399142)
  • Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781)
  • Thyrotoxic periodic paralysis ( 33105104)
  • TPE interval (response to exercise) ( 32386560)
  • TPE interval (resting) ( 32386560)
  • Triglyceride levels ( 32203549)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
  • White matter hyperintensity volume ( 33293549)
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
Interacting Genes 75 interacting genes: ACTA1 ACTN2 ADAM17 ADGRA2 ADGRA3 ADGRB1 ADRB1 AKAP5 ATP2B2 ATP2B4 BCR BEGAIN CACNG2 CALM2 CAMK2A CASK CNKSR2 CRHR1 CRIPT CTNNA1 DLG2 DLG3 DLGAP1 DLGAP3 DLGAP4 EPB41 ERBB4 EZR FZD4 FZD7 GDA GLS2 GNG13 GRIA1 GRIK2 GRIN1 GRIN2A GRIN2B GUCY1A2 HTR2A KCNA1 KCNA2 KCNA3 KCNA4 KCNA5 KCNAB1 KCNJ10 KCNJ12 KCNJ2 KCNJ4 KCNJ6 KHDRBS1 KIF13B KIF1B LCK LRP2 LRRC1 MAP1A MAPK12 MPP2 MRPS34 MYO6 PAX6 PBK PRKN PTEN SCN4A SCN5A SEMA4C STX4 TANC1 TJAP1 UBE3A WAS WNT3A 21 interacting genes: AKAP5 ARL13B CASK DLG1 DLG2 DLG3 DLG4 FLNA IL16 KCNJ11 KCNJ15 KCNJ16 KCNJ18 KCNJ4 KCNJ8 PATJ SDC3 SDCBP SEC22A TRAK2 UTP18
Entrez ID 1739 3759
HPRD ID 03007 02815
Ensembl ID ENSG00000075711 ENSG00000123700
Uniprot IDs A0A0C4DFT3 A0A590UJ08 B4DF78 Q12959 P63252
PDB IDs 1PDR 2M3M 2OQS 2X7Z 3LRA 3RL7 3RL8 3W9Y 4AMH 4G69 6SPZ
Enriched GO Terms of Interacting Partners?
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