CYP2D6 and CYP2C9

  • Number of citations of the paper that reports this interaction (PubMedID 19448135)
  • 27

CYP2D6

CYP2C9

Description cytochrome P450 family 2 subfamily D member 6 cytochrome P450 family 2 subfamily C member 9
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Intelligence ( 28530673)
  • Refractive error ( 32231278)
  • Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) ( 24528284)
  • Schizophrenia ( 25056061 29483656)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Blood metabolite levels ( 24816252)
  • Clopidogrel active metabolite levels ( 28207573)
  • Dehydroepiandrosterone sulphate levels ( 21533175)
  • Diastolic blood pressure ( 27841878)
  • glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292)
  • Immune response to smallpox vaccine (IL-6) ( 22542470)
  • Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102)
  • Pulse pressure ( 27841878)
  • Response to clopidogrel therapy ( 28207573 19706858)
  • Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) ( 24528284)
  • Serum metabolite levels ( 23093944)
  • Systolic blood pressure ( 27841878)
  • Warfarin maintenance dose ( 18535201 23755828 20833655 19300499 26265036)
Interacting Genes 3 interacting genes: CYB5A CYP2C9 POR 10 interacting genes: CDC37 CYP2D6 CYP3A4 ECSIT MAST1 POR RAB3D RNF32 STAMBP STAT5A
Entrez ID 1565 1559
HPRD ID 00487 03084
Ensembl ID ENSG00000100197 ENSG00000138109
Uniprot IDs C1ID52 P10635 Q5Y7H2 P11712 S5RV20
PDB IDs 2F9Q 3QM4 3TBG 3TDA 4WNT 4WNU 4WNV 4WNW 4XRY 4XRZ 5TFT 5TFU 6CSB 6CSD 1OG2 1OG5 1R9O 4NZ2 5A5I 5A5J 5K7K 5W0C 5X23 5X24 5XXI 6VLT
Enriched GO Terms of Interacting Partners?
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