CYP2C9 and STAT5A

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

CYP2C9

STAT5A

Description cytochrome P450 family 2 subfamily C member 9 signal transducer and activator of transcription 5A
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood metabolite levels ( 24816252)
  • Clopidogrel active metabolite levels ( 28207573)
  • Dehydroepiandrosterone sulphate levels ( 21533175)
  • Diastolic blood pressure ( 27841878)
  • glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292)
  • Immune response to smallpox vaccine (IL-6) ( 22542470)
  • Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102)
  • Pulse pressure ( 27841878)
  • Response to clopidogrel therapy ( 28207573 19706858)
  • Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) ( 24528284)
  • Serum metabolite levels ( 23093944)
  • Systolic blood pressure ( 27841878)
  • Warfarin maintenance dose ( 18535201 23755828 20833655 19300499 26265036)
Interacting Genes 10 interacting genes: CDC37 CYP2D6 CYP3A4 ECSIT MAST1 POR RAB3D RNF32 STAMBP STAT5A 72 interacting genes: AQP11 BMX BRCA1 BRCA2 BTK CBL CCR5 CD247 CEBPB CENPJ CRK CRKL CSNK2B CTLA4 CYP2C9 EGFR EP300 EPAS1 EPOR ERBB4 ESR1 ESR2 FBXW7 FN1 GHR GLUD1 GNB2 HELZ IL2RB IL2RG IL7R INSR JAK1 JAK2 JAK3 KIT LCK MAGEA12 MAPK1 MAPK3 MRPS6 NCOR2 NMI NR3C1 OLIG1 PDGFRA PDGFRB POM121C POU2F1 PPIB PPP2CA PRMT1 PRTFDC1 PTPN1 PTPN11 PTPN2 RBMX SHC1 SRC STAP2 STAT1 STAT3 STAT5B SYK TCF12 TEK TET2 TSLP TXNDC11 UGT2B4 WASH2P ZNF596
Entrez ID 1559 6776
HPRD ID 03084 03301
Ensembl ID ENSG00000138109 ENSG00000126561
Uniprot IDs P11712 S5RV20 A0A384N5W4 A0A7I2YQF1 A8K6I5 K7EK35 P42229 Q59GY7
PDB IDs 1OG2 1OG5 1R9O 4NZ2 5A5I 5A5J 5K7K 5W0C 5X23 5X24 5XXI 6VLT
Enriched GO Terms of Interacting Partners?
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