CYP2C9 and ECSIT

  • Number of citations of the paper that reports this interaction (PubMedID 21163940)
  • 36
  • Data Source:
  • BioGRID (two hybrid)

CYP2C9

ECSIT

Description cytochrome P450 family 2 subfamily C member 9 ECSIT signaling integrator
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood metabolite levels ( 24816252)
  • Clopidogrel active metabolite levels ( 28207573)
  • Dehydroepiandrosterone sulphate levels ( 21533175)
  • Diastolic blood pressure ( 27841878)
  • glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292)
  • Immune response to smallpox vaccine (IL-6) ( 22542470)
  • Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102)
  • Pulse pressure ( 27841878)
  • Response to clopidogrel therapy ( 28207573 19706858)
  • Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) ( 24528284)
  • Serum metabolite levels ( 23093944)
  • Systolic blood pressure ( 27841878)
  • Warfarin maintenance dose ( 18535201 23755828 20833655 19300499 26265036)
  • Presence of antiphospholipid antibodies ( 27098658)
Interacting Genes 10 interacting genes: CDC37 CYP2D6 CYP3A4 ECSIT MAST1 POR RAB3D RNF32 STAMBP STAT5A 61 interacting genes: A2M AP1M2 APOE APP BFSP2 BLMH C1orf109 CDC37 CEP55 CNN1 CORO2B CTNNA3 CYP2C18 CYP2C8 CYP2C9 DNAJB1 DTX2 DYNC1H1 ELAVL3 EXOC6 EXOSC1 FARSA FBXL12 FBXW4 GCDH GEM IFIT3 IFIT5 IMMT LONP1 LOXL4 MAGEB2 MARCHF2 MAST1 MKRN3 MRPL4 NDUFA13 NFKB1 NXF1 OGT PAXIP1 PI4K2A PRDX2 PSEN1 RAB3A RAD23A RELA RHEB RNF32 SELPLG SETDB1 SHFL SMAD1 SMAD4 SMURF1 STAMBPL1 STRN4 TARS3 TRAF6 TRIM59 TSSK3
Entrez ID 1559 51295
HPRD ID 03084 12225
Ensembl ID ENSG00000138109 ENSG00000130159
Uniprot IDs P11712 S5RV20 Q9BQ95
PDB IDs 1OG2 1OG5 1R9O 4NZ2 5A5I 5A5J 5K7K 5W0C 5X23 5X24 5XXI 6VLT
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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