PRICKLE1 and SMURF2

  • Number of citations of the paper that reports this interaction (PubMedID 19379695)
  • 158
  • Data Source:
  • HPRD (in vivo)

PRICKLE1

SMURF2

Description prickle planar cell polarity protein 1 SMAD specific E3 ubiquitin protein ligase 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autoimmune thyroid diseases (Graves disease or Hashimoto's thyroiditis) ( 22922229)
  • Blood urea nitrogen levels ( 31152163)
  • Colorectal cancer ( 30529582 31826910)
  • Endometrial cancer (Non-endometrioid histology) ( 30093612)
  • Graves' disease ( 22922229)
  • Heart failure ( 20445134)
  • Hip circumference adjusted for BMI ( 28552196)
  • Impulsivity (non-planning) ( 30718321)
  • Inferior parietal cortex volume ( 31530798)
  • Multiple sclerosis ( 31604244)
  • Night sleep phenotypes ( 27126917)
  • Parkinson's disease ( 27182965)
  • Refractive error ( 32231278)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
  • Cardiac troponin-I levels ( 31014085)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Joint mobility (Beighton score) ( 27182965)
  • Lung function (FEV1/FVC) ( 30804560)
  • Lung function (FVC) ( 30804560)
  • Periodontitis (Mean PAL) ( 24024966)
Interacting Genes 14 interacting genes: ANO6 ARID2 BYSL CECR2 HIP1R JRK KIF9 LRRK2 PPP3CB PRPF31 SMURF2 TYR UTP14C VIP 91 interacting genes: ABRAXAS2 ACBD3 ACOX3 AIMP2 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CNKSR2 CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FKBP4 FLNB FOXJ1 FUBP1 GNG2 HDGFL3 ING2 IRF3 IRF8 ITGB1BP1 KLF5 LAPTM5 LATS1 LMNA MAVS NEK6 NKIRAS1 NRAS PDE4B PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RPS27A RRAS2 RTN4IP1 RUNX2 RUNX3 SF3A2 SIRT1 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNCA SNRNP70 SOCS6 SPART SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TOP2A TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D2 UBE2D3 UBE2L3 USP15 XPO1 YY1 ZBTB44
Entrez ID 144165 64750
HPRD ID 16341 06901
Ensembl ID ENSG00000139174 ENSG00000108854
Uniprot IDs A0A024R0W7 B3KVG3 B3KVG6 Q96MT3 Q96DE7 Q9HAU4
PDB IDs 1ZVD 2DJY 2JQZ 2KXQ 2LTZ 6FX4
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?