SMURF2 and RASL12

  • Number of citations of the paper that reports this interaction (PubMedID 15761153)
  • 269
  • Data Source:
  • HPRD (in vivo)

SMURF2

RASL12

Description SMAD specific E3 ubiquitin protein ligase 2 RAS like family 12
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cardiac troponin-I levels ( 31014085)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Joint mobility (Beighton score) ( 27182965)
  • Lung function (FEV1/FVC) ( 30804560)
  • Lung function (FVC) ( 30804560)
  • Periodontitis (Mean PAL) ( 24024966)
  • White matter hyperintensity volume ( 33293549)
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
  • White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Interacting Genes 91 interacting genes: ABRAXAS2 ACBD3 ACOX3 AIMP2 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CNKSR2 CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FKBP4 FLNB FOXJ1 FUBP1 GNG2 HDGFL3 ING2 IRF3 IRF8 ITGB1BP1 KLF5 LAPTM5 LATS1 LMNA MAVS NEK6 NKIRAS1 NRAS PDE4B PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RPS27A RRAS2 RTN4IP1 RUNX2 RUNX3 SF3A2 SIRT1 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNCA SNRNP70 SOCS6 SPART SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TOP2A TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D2 UBE2D3 UBE2L3 USP15 XPO1 YY1 ZBTB44 12 interacting genes: ACVR1 APP BMPR1B CLK1 FHL2 FHL3 SMAD1 SMAD2 SMAD3 SMAD4 SMURF2 TGFBR1
Entrez ID 64750 51285
HPRD ID 06901 15217
Ensembl ID ENSG00000108854 ENSG00000103710
Uniprot IDs Q96DE7 Q9HAU4 A0A024R5Y3 Q9NYN1
PDB IDs 1ZVD 2DJY 2JQZ 2KXQ 2LTZ 6FX4 3C5C
Enriched GO Terms of Interacting Partners?
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