FUNDC1 and TUFM

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		FUNDC1	TUFM
Description		FUN14 domain containing 1	Tu translation elongation factor, mitochondrial
Image
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Integral Component Of Mitochondrial Outer Membrane	Mitochondrion Membrane Mitochondrial Nucleoid Synapse Extracellular Exosome
	Molecular Function	Protein Binding	RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding
	Biological Process	Autophagy Of Mitochondrion Response To Hypoxia Response To Organonitrogen Compound	Translational Elongation Response To Ethanol Mitochondrial Translational Elongation
Pathways		Receptor Mediated Mitophagy	Mitochondrial translation elongation
Drugs			Zinc Guanosine-5'-Diphosphate Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Facial morphology (factor 22) ( 28441456) Personality dimensions ( 18957941)	Alcohol consumption (drinks per week) ( 30643258) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat percentage ( 26833246) Body mass index ( 20935630) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908) Educational attainment ( 25201988) Estimated glomerular filtration rate ( 31152163) Extremely high intelligence ( 29520040) Hip circumference adjusted for BMI ( 25673412) Inflammatory bowel disease ( 28067908) Intelligence ( 28530673) Lamb consumption ( 32066663) Walking pace ( 33128006)
Interacting Genes		15 interacting genes: CTBP1 CTBP2 EHHADH GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MARCHF5 MTERF3 SENP2 SH3GLB1 SLC25A46 SNX1 TUFM YES1	23 interacting genes: ARL6IP1 ASPH ATP6V1A CMTM5 DGAT2L6 DOC2A EXOSC6 FAM9B FUNDC1 HMBOX1 LINC01554 MTIF3 MYH9 OGT PCAT1 PDGFRB PPP1R16B PTEN RHBDD2 SYP TAOK2 TNFRSF10D ZDHHC15
Entrez ID		139341	7284
HPRD ID		06658	03861
Ensembl ID		ENSG00000069509	ENSG00000178952
Uniprot IDs		Q8IVP5	A0A384ME17 P49411
PDB IDs		2N9X 5GMV	7A5G
Enriched GO Terms of Interacting Partners?
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