TRIM50 and L3MBTL2

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

TRIM50

L3MBTL2

Description tripartite motif containing 50 L3MBTL histone methyl-lysine binding protein 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
  • Adventurousness ( 30643258)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Anxiety ( 33859377)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Crohn's disease ( 26192919)
  • Depression ( 29700475)
  • General risk tolerance (MTAG) ( 30643258)
  • Inflammatory bowel disease ( 26192919)
  • Lamb consumption ( 32066663)
  • Major depressive disorder ( 27479909)
  • Neuroticism ( 29255261 27918536)
  • Refractive error ( 32231278)
  • Schizophrenia ( 25056061 29483656)
Interacting Genes 40 interacting genes: ARHGAP45 CDK18 CLK2 EFHC2 EPM2AIP1 FAM221B GCC1 HDAC6 IQUB KLHL2 L3MBTL2 LNX1 MEOX2 PIAS2 PLA2G6 RAD23A RSPH14 SNAI1 SPG21 SRC TEPSIN TRAF2 TRIM27 TSGA10IP TSSK3 UBASH3A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2N UBTD1 USP2 XAF1 ZNF438 ZNF620 53 interacting genes: AMOTL2 BEND7 BHLHB9 BIVM CARD9 CCDC106 CCDC33 CEP76 CYB5R3 EFHC2 EIF4ENIF1 FAM217B GAS8 GKAP1 GOLGA2 H3C1 H4C1 HSF2BP LNX2 MEAF6 MEOX1 MPP3 NRF1 PAICS PHF10 PIAS1 PICK1 POU6F2 PRKAR1B RBAK REL SSUH2 STAC3 STAM2 TAFA5 TAX1BP1 TBC1D9B TEKT1 THAP1 THAP11 TLE5 TNNI1 TRIM42 TRIM50 TSPYL1 TUBGCP6 XPNPEP3 ZBTB26 ZBTB48 ZFP64 ZFY ZNF467 ZNF829
Entrez ID 135892 83746
HPRD ID 15566 13954
Ensembl ID ENSG00000146755 ENSG00000100395
Uniprot IDs B7ZLG2 Q2M204 Q86XT4 A0A0S2Z5X6 Q969R5
PDB IDs 2W0T 3CEY 3F70
Enriched GO Terms of Interacting Partners?
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