L3MBTL2 and STAC3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		L3MBTL2	STAC3
Description		L3MBTL histone methyl-lysine binding protein 2	SH3 and cysteine rich domain 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleoplasm Cytosol Voltage-gated Calcium Channel Complex T-tubule Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Synapse
	Molecular Function	Chromatin Binding Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Chromatin Organization Negative Regulation Of Transcription, DNA-templated	Skeletal Muscle Contraction Neuromuscular Synaptic Transmission Intracellular Signal Transduction Skeletal Muscle Fiber Development Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety ( 33859377) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Lamb consumption ( 32066663) Major depressive disorder ( 27479909) Neuroticism ( 29255261 27918536) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Glycated hemoglobin levels ( 34059833) Schizophrenia ( 25056061 29483656)
Interacting Genes		53 interacting genes: AMOTL2 BEND7 BHLHB9 BIVM CARD9 CCDC106 CCDC33 CEP76 CYB5R3 EFHC2 EIF4ENIF1 FAM217B GAS8 GKAP1 GOLGA2 H3C1 H4C1 HSF2BP LNX2 MEAF6 MEOX1 MPP3 NRF1 PAICS PHF10 PIAS1 PICK1 POU6F2 PRKAR1B RBAK REL SSUH2 STAC3 STAM2 TAFA5 TAX1BP1 TBC1D9B TEKT1 THAP1 THAP11 TLE5 TNNI1 TRIM42 TRIM50 TSPYL1 TUBGCP6 XPNPEP3 ZBTB26 ZBTB48 ZFP64 ZFY ZNF467 ZNF829	38 interacting genes: ANKRD36 BAZ2B C1orf35 CSNK2A1 DIP2A EAF1 EAF2 ENKD1 FAM124A FAM133A FAM90A1 FAM9A FGF11 FGF12 GAS8 GIGYF1 GRB7 HMGXB4 INO80B JMJD6 L3MBTL2 MAB21L3 MFAP1 NKAPD1 NSD3 PPARA RPL22 RPL9 RPS25 SPANXN2 SPANXN3 SREK1IP1 TCEA2 TNFAIP8L1 U2AF2 VCX2 ZCCHC10 ZGPAT
Entrez ID		83746	246329
HPRD ID		13954	11606
Ensembl ID		ENSG00000100395	ENSG00000185482
Uniprot IDs		A0A0S2Z5X6 Q969R5	A0A024RB38 Q96MF2
PDB IDs		2W0T 3CEY 3F70	2DB6 6B29 6UY7 6UY8 6UY9
Enriched GO Terms of Interacting Partners?
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