TRIM50 and GCC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRIM50	GCC1
Description		tripartite motif containing 50	GRIP and coiled-coil domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Golgi Trans Cisterna Golgi Membrane Golgi Apparatus Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding Small GTPase Binding
	Biological Process	Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IL-12p40) ( 22610502)	Feeling worry ( 29500382) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Medication adherence in chronic diseases ( 25317111) Refractive error ( 32231278) Type 2 diabetes ( 26818947 22158537 30718926)
Interacting Genes		40 interacting genes: ARHGAP45 CDK18 CLK2 EFHC2 EPM2AIP1 FAM221B GCC1 HDAC6 IQUB KLHL2 L3MBTL2 LNX1 MEOX2 PIAS2 PLA2G6 RAD23A RSPH14 SNAI1 SPG21 SRC TEPSIN TRAF2 TRIM27 TSGA10IP TSSK3 UBASH3A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2N UBTD1 USP2 XAF1 ZNF438 ZNF620	73 interacting genes: ABI2 ADGRE5 AMOTL2 APP ARL1 ATF4 ATN1 BIRC2 BRCA1 C1orf94 CCDC33 CCDC85B CEP57 CEP70 COIL CPSF7 CRHR2 DISC1 DNAJA3 FAM71F2 FAM83A FBF1 FBXO28 FIGNL1 FOSL1 GAS8 GLI1 GOLGA2 GTF2I HDX HILPDA ICA1L IKBKG ITSN1 KATNAL1 KDM1A KHSRP KIAA0753 KIAA1217 KIF5B LCA5 LZTS2 MCRS1 MED4 MEOX1 MID2 NAB2 NAV1 NECAB2 NINL OIP5 PAK5 PCDHA1 PPP1R18 PPP1R27 PRPF18 RBM28 RUNX1 SMARCA2 SMARCD1 SPOP TFIP11 TLE5 TP53BP2 TRIM29 TRIM50 TSC1 USHBP1 UTP14C XIAP ZC4H2 ZFP90 ZNF276
Entrez ID		135892	79571
HPRD ID		15566	07599
Ensembl ID		ENSG00000146755	ENSG00000179562
Uniprot IDs		B7ZLG2 Q2M204 Q86XT4	A4D0Z4 Q96CN9
PDB IDs
Enriched GO Terms of Interacting Partners?
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