MAP3K8 and LYZL2

		MAP3K8	LYZL2
Description		mitogen-activated protein kinase kinase kinase 8	lysozyme like 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Extracellular Region
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Lysozyme Activity
	Biological Process	MAPK Cascade Protein Phosphorylation Cell Cycle T Cell Costimulation	Metabolic Process
Pathways		CD28 dependent PI3K/Akt signaling MAP3K8 (TPL2)-dependent MAPK1/3 activation MAP3K8 (TPL2)-dependent MAPK1/3 activation
Drugs
Diseases
GWAS		Asthma ( 32296059) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Systemising ( 31508503) Ulcerative colitis ( 28067908)	Bone mineral density (femoral neck) ( 26911590) Dental caries ( 23064961)
Interacting Genes		26 interacting genes: ACP6 ACY3 ADAM10 AKT1 BMPR2 CD40 CHUK GAD2 JCAD LYZL2 MAP2K1 MAP2K4 MAP3K14 MTPAP NFKB1 NFKB2 PARD3 PDK2 RANGAP1 REL RELA RIPK1 STIP1 TNIP2 TRAF2 TRAF6	1 interacting genes: MAP3K8
Entrez ID		1326	119180
HPRD ID		01863	14337
Ensembl ID		ENSG00000107968	ENSG00000151033
Uniprot IDs		P41279 Q6FG25	A0A080YUZ9 Q7Z4W2
PDB IDs		4Y83 4Y85 5IU2
Enriched GO Terms of Interacting Partners?
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