MTERF4 and OSGIN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MTERF4	OSGIN1
Description		mitochondrial transcription termination factor 4	oxidative stress induced growth inhibitor 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Mitochondrial Large Ribosomal Subunit Cytosol	Cellular_component
	Molecular Function	Double-stranded DNA Binding Protein Binding RRNA Binding	Protein Binding Growth Factor Activity
	Biological Process	Regulation Of Transcription, DNA-templated RRNA Processing Mitochondrial Transcription Protein Targeting To Mitochondrion Heart Development Ribosome Assembly Camera-type Eye Development	Signal Transduction Cell Differentiation Negative Regulation Of Cell Growth Regulation Of Cell Migration Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process
Pathways		rRNA modification in the mitochondrion
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) LDL cholesterol ( 30275531) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Pursuit maintenance gain ( 29064472) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		10 interacting genes: APP ATXN1 BANP CIDEB DGAT2L6 EMD FOS OSGIN1 TNFRSF10D UBC	47 interacting genes: AKT1 ARNT2 ATM BCAR3 BEND7 BTBD2 CAPN3 CCDC33 CENPN CRX DECR2 DNAJA3 FGFR4 GCLM HOMEZ IKBKG IKZF3 INCA1 KATNBL1 KRAS KRT75 LNX1 MEI4 MEIS2 MEOX1 MEOX2 MTERF4 PAX5 PDE4A PDE4C PICK1 POLDIP3 POLR2G PPM1D PTEN REL SAXO1 SMARCB1 SORBS3 TCF12 TCF4 TLE5 TRIM54 XRCC3 ZBTB42 ZC2HC1C ZKSCAN4
Entrez ID		130916	29948
HPRD ID		14699	06412
Ensembl ID		ENSG00000122085	ENSG00000140961
Uniprot IDs		B4DFP7 Q7Z6M4	Q9UJX0
PDB IDs		4FP9 4FZV
Enriched GO Terms of Interacting Partners?
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