MRPL10 and USP22

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)

		MRPL10	USP22
Description		mitochondrial ribosomal protein L10	ubiquitin specific peptidase 22
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Large Ribosomal Subunit Ribonucleoprotein Complex	SAGA Complex Nucleoplasm
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	Transcription Coactivator Activity Thiol-dependent Deubiquitinase Protein Binding Zinc Ion Binding H4 Histone Acetyltransferase Activity Enzyme Binding Nuclear Receptor Coactivator Activity
	Biological Process	Translation	Ubiquitin-dependent Protein Catabolic Process Cell Cycle Embryo Development Ending In Birth Or Egg Hatching Histone Ubiquitination Histone Deubiquitination Protein Deubiquitination Histone H4 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Mitotic Cell Cycle
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	HATs acetylate histones Ub-specific processing proteases
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Asthma ( 31619474) Body mass index ( 26426971)	Body mass index ( 26426971) Mosquito bite size ( 28199695)
Interacting Genes		8 interacting genes: ACTN2 APP FAM9B KLHL12 PNMA1 REL TCF4 USP22	17 interacting genes: AASDHPPT ATXN7 ATXN7L3 B9D1 BAG4 H2AC20 H2BC21 HEXA MRPL10 MRPL44 MTUS2 PSME1 PTGS2 RCAN1 SCFD1 SIRT1 UBC
Entrez ID		124995	23326
HPRD ID		14738	19411
Ensembl ID		ENSG00000159111	ENSG00000124422
Uniprot IDs		Q7Z7H8	Q9UPT9
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K
Enriched GO Terms of Interacting Partners?
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