GGT6 and FAIM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GGT6	FAIM2
Description		gamma-glutamyltransferase 6	Fas apoptotic inhibitory molecule 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Extracellular Exosome	Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane Membrane Raft Postsynaptic Membrane
	Molecular Function	Molecular_function Protein Binding Glutathione Hydrolase Activity Hypoglycin A Gamma-glutamyl Transpeptidase Activity Leukotriene C4 Gamma-glutamyl Transferase Activity	Protein Binding
	Biological Process	Proteolysis Glutathione Biosynthetic Process Biological_process Leukotriene D4 Biosynthetic Process	Response To Ischemia Apoptotic Process Cerebellum Development Cerebellar Purkinje Cell Layer Development Cerebellar Granular Layer Development Cerebellar Purkinje Cell Differentiation Negative Regulation Of Apoptotic Process Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways		Glutathione synthesis and recycling Aflatoxin activation and detoxification
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 28118524) Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive) ( 28118524)	Adult body size ( 32376654) Alcohol consumption (drinks per week) ( 30643258) Blood urea nitrogen levels ( 31152163) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) BMI in smokers ( 28443625) Body fat mass ( 28552196) Body mass index ( 28552196 19079260 28892062 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Body size at age 10 ( 32376654) Breast size ( 27182965) Childhood body mass index ( 26604143) Hip circumference ( 28552196 25673412) Menarche (age at onset) ( 27182965) Obese vs. thin ( 30677029) Obesity (extreme) ( 30677029) Obsessive-compulsive disorder ( 22889921) Trunk fat mass ( 28552196) Type 2 diabetes ( 32499647) Urate levels ( 31578528) Waist circumference ( 28552196 19557197) Weight ( 28552196 19079260)
Interacting Genes		11 interacting genes: ADAM33 BMP10 ENTPD3 FAIM2 FAM3C GRINA NOTCH3 PIGS SEC22A TMBIM1 TNMD	7 interacting genes: EPN2 ERBB2 FAS GGT6 OS9 SLC22A2 STK11
Entrez ID		124975	23017
HPRD ID		08293	09184
Ensembl ID		ENSG00000167741	ENSG00000135472
Uniprot IDs		B4DKN3 J3KPJ0 Q6P531 Q6ZPD7	Q9BWQ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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