GGT6 and TMBIM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GGT6	TMBIM1
Description		gamma-glutamyltransferase 6	transmembrane BAX inhibitor motif containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Extracellular Exosome	Lysosomal Membrane Golgi Apparatus Plasma Membrane Endosome Membrane Integral Component Of Membrane Specific Granule Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding Glutathione Hydrolase Activity Hypoglycin A Gamma-glutamyl Transpeptidase Activity Leukotriene C4 Gamma-glutamyl Transferase Activity	Death Receptor Binding Protein Binding
	Biological Process	Proteolysis Glutathione Biosynthetic Process Biological_process Leukotriene D4 Biosynthetic Process	Negative Regulation Of Catalytic Activity Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Fas Signaling Pathway Negative Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Blood Vessel Remodeling
Pathways		Glutathione synthesis and recycling Aflatoxin activation and detoxification	Neutrophil degranulation
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 28118524) Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive) ( 28118524)	Colorectal cancer ( 28960316) Colorectal cancer or advanced adenoma ( 30510241) Gallstone disease ( 30504769) Glycated hemoglobin levels ( 34059833) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908 23128233) Red cell distribution width ( 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		11 interacting genes: ADAM33 BMP10 ENTPD3 FAIM2 FAM3C GRINA NOTCH3 PIGS SEC22A TMBIM1 TNMD	13 interacting genes: B3GALNT2 BIK CD33 F2RL1 GGT6 PROK2 RCHY1 RIC3 SLC10A1 SOCS5 TMEM242 TRIM55 TRIM63
Entrez ID		124975	64114
HPRD ID		08293	17884
Ensembl ID		ENSG00000167741	ENSG00000135926
Uniprot IDs		B4DKN3 J3KPJ0 Q6P531 Q6ZPD7	A0A024R472 B3KSM0 B4DUD2 Q969X1
PDB IDs
Enriched GO Terms of Interacting Partners?
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