ADSS1 and LYAR

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ADSS1	LYAR
Description		adenylosuccinate synthase 1	Ly1 antibody reactive
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol	Photoreceptor Outer Segment Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Magnesium Ion Binding GTPase Activity Adenylosuccinate Synthase Activity GTP Binding Phosphate Ion Binding Identical Protein Binding Actin Filament Binding	DNA Binding RNA Binding Protein Binding Identical Protein Binding Metal Ion Binding DNA-binding Transcription Factor Binding Transcription Regulator Inhibitor Activity
	Biological Process	Immune System Process AMP Biosynthetic Process Aspartate Metabolic Process Glutamine Metabolic Process Response To Muscle Activity Response To Starvation 'de Novo' AMP Biosynthetic Process IMP Metabolic Process Cellular Response To Electrical Stimulus Cellular Response To Xenobiotic Stimulus	Negative Regulation Of Transcription By RNA Polymerase II RRNA Processing Innate Immune Response Negative Regulation Of Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase I Erythrocyte Development Positive Regulation Of Phagocytosis
Pathways		Purine ribonucleoside monophosphate biosynthesis
Drugs		Aspartic acid Hadacidin 6-O-Phosphoryl Inosine Monophosphate Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate Adenylosuccinic acid Inosinic Acid Alanosine
Diseases
GWAS			Disease progression in age-related macular degeneration ( 29346644)
Interacting Genes		3 interacting genes: AZIN1 LYAR TRMT61A	14 interacting genes: ADSS1 BEND7 CD2 FGF18 GSK3B OGT PHF20L1 PRKRA SDCBP2 SREK1IP1 TERF1 TERF2 ZBTB16 ZHX1
Entrez ID		122622	55646
HPRD ID		12433	10064
Ensembl ID		ENSG00000185100	ENSG00000145220
Uniprot IDs		B3KTV4 Q8N142	Q9NX58
PDB IDs		2GJO	6ZMI 6ZMO 6ZVH
Enriched GO Terms of Interacting Partners?
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