ADSS1 and AZIN1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ADSS1	AZIN1
Description		adenylosuccinate synthase 1	antizyme inhibitor 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytoplasm Cytosol
	Molecular Function	Magnesium Ion Binding GTPase Activity Adenylosuccinate Synthase Activity GTP Binding Phosphate Ion Binding Identical Protein Binding Actin Filament Binding	Ornithine Decarboxylase Activity Protein Binding Ornithine Decarboxylase Activator Activity
	Biological Process	Immune System Process AMP Biosynthetic Process Aspartate Metabolic Process Glutamine Metabolic Process Response To Muscle Activity Response To Starvation 'de Novo' AMP Biosynthetic Process IMP Metabolic Process Cellular Response To Electrical Stimulus Cellular Response To Xenobiotic Stimulus	Putrescine Biosynthetic Process From Ornithine Negative Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Positive Regulation Of Polyamine Transmembrane Transport
Pathways		Purine ribonucleoside monophosphate biosynthesis	Regulation of ornithine decarboxylase (ODC)
Drugs		Aspartic acid Hadacidin 6-O-Phosphoryl Inosine Monophosphate Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate Adenylosuccinic acid Inosinic Acid Alanosine
Diseases
GWAS			Airway imaging phenotypes ( 26030696) Apolipoprotein A1 levels ( 32203549) Granulocyte count ( 27863252) HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Neutrophil count ( 27863252) PR interval ( 32439900) QT interval ( 24952745) Serum alkaline phosphatase levels ( 33547301) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) TPE interval (resting) ( 32386560) Waist circumference adjusted for body mass index ( 28552196) White blood cell count ( 32888494)
Interacting Genes		3 interacting genes: AZIN1 LYAR TRMT61A	9 interacting genes: ABCC2 ADSS1 ARNTL CDKN2A FANCA FANCC KHDRBS1 OAZ3 SORCS3
Entrez ID		122622	51582
HPRD ID		12433	07443
Ensembl ID		ENSG00000185100	ENSG00000155096
Uniprot IDs		B3KTV4 Q8N142	A0A024R9C7 B3KTF6 O14977
PDB IDs		2GJO	4ZGZ
Enriched GO Terms of Interacting Partners?
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