AZIN1 and SORCS3

		AZIN1	SORCS3
Description		antizyme inhibitor 1	sortilin related VPS10 domain containing receptor 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Membrane Integral Component Of Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Ornithine Decarboxylase Activity Protein Binding Ornithine Decarboxylase Activator Activity	Protein Binding Neuropeptide Receptor Activity
	Biological Process	Putrescine Biosynthetic Process From Ornithine Negative Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Positive Regulation Of Polyamine Transmembrane Transport	Neuropeptide Signaling Pathway Learning Memory Regulation Of Long-term Synaptic Depression
Pathways		Regulation of ornithine decarboxylase (ODC)
Drugs
Diseases
GWAS		Airway imaging phenotypes ( 26030696) Apolipoprotein A1 levels ( 32203549) Granulocyte count ( 27863252) HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Neutrophil count ( 27863252) PR interval ( 32439900) QT interval ( 24952745) Serum alkaline phosphatase levels ( 33547301) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) TPE interval (resting) ( 32386560) Waist circumference adjusted for body mass index ( 28552196) White blood cell count ( 32888494)	Age at first birth ( 34211149) Age at first sexual intercourse ( 34211149) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Attention deficit hyperactivity disorder ( 30478444) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Depression ( 33859377 29700475) Diabetic kidney disease ( 26305897) Diastolic blood pressure ( 30224653 33230300) Feeling miserable ( 29500382) Gastroesophageal reflux disease ( 34187846) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Intelligence (MTAG) ( 29326435) Major depressive disorder ( 27479909) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Metabolite levels ( 23823483) Mood instability ( 31168069) Multisite chronic pain ( 33830993 31194737) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600) Pulse pressure ( 33230300) Rosacea symptom severity ( 29771307) Schizophrenia ( 33169155) Subclinical trait of interstitial lung disease (basilar percentage of high attenuation areas on CT scan) ( 28521775) Systolic blood pressure ( 33230300 30578418)
Interacting Genes		9 interacting genes: ABCC2 ADSS1 ARNTL CDKN2A FANCA FANCC KHDRBS1 OAZ3 SORCS3	7 interacting genes: ACSM6 ATXN1 AZIN1 F8 IDE NGF RGS14
Entrez ID		51582	22986
HPRD ID		07443	12100
Ensembl ID		ENSG00000155096	ENSG00000156395
Uniprot IDs		A0A024R9C7 B3KTF6 O14977	Q86XB2 Q9UPU3
PDB IDs		4ZGZ
Enriched GO Terms of Interacting Partners?
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