MED12L and MSRB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MED12L	MSRB3
Description		mediator complex subunit 12L	methionine sulfoxide reductase B3
Image		No pdb structure
GO Annotations	Cellular Component	Mediator Complex	Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol
	Molecular Function	Transcription Coactivator Activity Protein Binding Beta-catenin Binding	Protein Binding Zinc Ion Binding Peptide-methionine (R)-S-oxide Reductase Activity L-methionine-(R)-S-oxide Reductase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated	Response To Oxidative Stress Protein Repair
Pathways			Protein repair
Drugs
Diseases
GWAS		Chronotype ( 30696823) Eosinophil counts ( 32888494) Epstein-Barr virus EBNA-1 antibody levels ( 33204752) Heschl's gyrus morphology ( 25130324) Lymphocyte counts ( 32888494) Parkinson's disease ( 32201043) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Trunk fat mass ( 28552196) White blood cell count ( 32888494)	Antisaccade task score ( 31596458) Birth weight ( 31043758) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical volume ( 32963231) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) Differentiated thyroid cancer ( 28703219) FEV1 ( 30804560) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Height ( 31562340) Hippocampal fissure volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA1 volume (corrected for total hippocampal volume) ( 30279459) Hippocampal subfield CA3 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal volume ( 28098162 22504421) Lung function (FEV1) ( 28166213) Lung function (FVC) ( 30804560) Papillary thyroid cancer ( 28703219) Peak expiratory flow ( 30804560) Post bronchodilator FEV1/FVC ratio ( 26634245) Primary tooth development (number of teeth) ( 23704328 20195514) Primary tooth development (time to first tooth eruption) ( 23704328 20195514) Subcortical brain region volumes ( 25607358) Subiculum volume ( 30279459) Temperament ( 22832960) Temporal lobe volume ( 31396565) Total hippocampal volume ( 30279459) Type 2 diabetes nephropathy ( 21150874)
Interacting Genes		8 interacting genes: AR CKS1B IGSF10 LAMTOR5 MAPK9 MSRB3 TLE5 TTC23	32 interacting genes: ASB13 BANP CTBP2 EEF1AKMT3 EFEMP1 EIF6 FAM168B FHL3 GOLGA2 KRT31 KRT34 KRT40 LCN2 LNX2 MAPK8IP2 MED12L METTL15 METTL21A MGLL PICK1 PLEKHG4 POU6F2 PRDM4 REL TCF4 TRIM23 TRIM55 TRIM63 TRIP6 UFSP1 WDR61 ZMYND12
Entrez ID		116931	253827
HPRD ID		10278	14785
Ensembl ID		ENSG00000144893	ENSG00000174099
Uniprot IDs		B3KXY0 Q86YW9	Q8IXL7
PDB IDs			6QA0
Enriched GO Terms of Interacting Partners?
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