MSRB3 and METTL21A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MSRB3	METTL21A
Description		methionine sulfoxide reductase B3	methyltransferase 21A, HSPA lysine
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol	Nucleoplasm Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding Zinc Ion Binding Peptide-methionine (R)-S-oxide Reductase Activity L-methionine-(R)-S-oxide Reductase Activity	Protein Binding Protein Methyltransferase Activity Protein-lysine N-methyltransferase Activity Hsp70 Protein Binding Heat Shock Protein Binding ATPase Binding
	Biological Process	Response To Oxidative Stress Protein Repair	Protein Methylation Peptidyl-lysine Methylation Regulation Of ATPase Activity
Pathways		Protein repair	Protein methylation
Drugs
Diseases
GWAS		Antisaccade task score ( 31596458) Birth weight ( 31043758) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical volume ( 32963231) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) Differentiated thyroid cancer ( 28703219) FEV1 ( 30804560) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Height ( 31562340) Hippocampal fissure volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA1 volume (corrected for total hippocampal volume) ( 30279459) Hippocampal subfield CA3 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal volume ( 28098162 22504421) Lung function (FEV1) ( 28166213) Lung function (FVC) ( 30804560) Papillary thyroid cancer ( 28703219) Peak expiratory flow ( 30804560) Post bronchodilator FEV1/FVC ratio ( 26634245) Primary tooth development (number of teeth) ( 23704328 20195514) Primary tooth development (time to first tooth eruption) ( 23704328 20195514) Subcortical brain region volumes ( 25607358) Subiculum volume ( 30279459) Temperament ( 22832960) Temporal lobe volume ( 31396565) Total hippocampal volume ( 30279459) Type 2 diabetes nephropathy ( 21150874)	HDL cholesterol levels ( 32203549) Opioid sensitivity ( 23183491) Systolic blood pressure ( 28135244 28739976 30578418)
Interacting Genes		32 interacting genes: ASB13 BANP CTBP2 EEF1AKMT3 EFEMP1 EIF6 FAM168B FHL3 GOLGA2 KRT31 KRT34 KRT40 LCN2 LNX2 MAPK8IP2 MED12L METTL15 METTL21A MGLL PICK1 PLEKHG4 POU6F2 PRDM4 REL TCF4 TRIM23 TRIM55 TRIM63 TRIP6 UFSP1 WDR61 ZMYND12	17 interacting genes: ARPC4 ATRIP DNAH7 GIGYF2 HSPA1A HSPA5 HSPA8 LNX1 LZTS1 MEI4 MEOX2 MSRB3 PFDN5 ZBED8 ZNF620 ZNF655 ZRANB1
Entrez ID		253827	151194
HPRD ID		14785	14090
Ensembl ID		ENSG00000174099	ENSG00000144401
Uniprot IDs		Q8IXL7	C9JES0 H7BXH9 Q8WXB1
PDB IDs		6QA0	4LEC
Enriched GO Terms of Interacting Partners?
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