LENG8 and MIA3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LENG8	MIA3
Description		leukocyte receptor cluster member 8	MIA SH3 domain ER export factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding	Protein Binding Cargo Receptor Activity
	Biological Process		Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Leukocyte Migration Exocytosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endocytosis Endoplasmic Reticulum Organization Negative Regulation Of Cell Adhesion Protein Secretion Protein Transport Negative Regulation Of Cell Migration Vesicle Cargo Loading Wound Healing Lipoprotein Transport Protein Localization To Endoplasmic Reticulum Exit Site COPII-coated Vesicle Cargo Loading Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Lymphocyte Migration
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Cargo concentration in the ER Post-translational protein phosphorylation
Drugs
Diseases
GWAS			Coronary artery disease ( 32469254 29212778 30104761 26343387 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 17634449 21378990) Myocardial infarction ( 33532862 26343387) Myocardial infarction (early onset) ( 19198609)
Interacting Genes		49 interacting genes: ANKHD1 ARID5A ATN1 BAG3 C10orf55 CAMK2A CEP70 CFAP53 COG2 CPSF7 CYSRT1 DMRTB1 DVL3 FAM166B GSE1 HMGXB4 HNRNPM IKBKG INCA1 INTS11 KDM1A LASP1 MAGED1 MAPK1IP1L MIA3 MSX2 MYOZ3 NCBP3 NUTM2F PCID2 PER2 PRDM16 PRMT5 PRMT6 PYGO1 RHOXF2 SMARCB1 SMN1 SMYD1 SNRPA SOCS7 SUV39H1 TFG TLE5 TNIP1 TRAF4 TSG101 VGLL3 ZNF34	16 interacting genes: CACNA1A CEP55 CLIC3 COL7A1 FXR2 HOMER3 HSD17B14 ITGAX LENG8 MTNR1B NCK2 PRDM14 SEC16A SEC23A SEC24C TRIM27
Entrez ID		114823	375056
HPRD ID		11226	18918
Ensembl ID		ENSG00000167615	ENSG00000154305
Uniprot IDs		A0A024R4R9 C9JMY0 Q96PV6	Q5JRA6
PDB IDs			5KYN 5KYU 5KYW
Enriched GO Terms of Interacting Partners?
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