GTF2A1L and TLX2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		GTF2A1L	TLX2
Description		general transcription factor IIA subunit 1 like	T cell leukemia homeobox 2
Image		No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIA Complex Cytoplasm	Chromatin Cellular_component Nucleus Cytoplasm
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Cognition	Mesoderm Formation Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Enteric Nervous System Development Animal Organ Development Negative Regulation Of Dendrite Morphogenesis
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Hepcidin/ferritin ratio ( 27846281) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Joint mobility (Beighton score) ( 27182965) Laterality in neovascular age-related macular degeneration ( 28775256) Polycystic ovary syndrome ( 21151128)
Interacting Genes		25 interacting genes: ASCL3 ATF4 CEBPE CSNK2A1 CSNK2A2 EMX1 EMX2 GAB1 GTF2A2 HMG20A HOXA5 HOXC11 HOXC9 ID3 MAFF MAFG NKX2-3 PAX9 RBFOX2 SIX6 SUB1 TBP TLX2 TLX3 ZBTB3	11 interacting genes: GTF2A1L IRF6 IRF9 KRTAP6-2 MCM4 MEIS1 POU2F1 POU6F2 TLE1 YWHAH ZNF502
Entrez ID		11036	3196
HPRD ID		05640	07254
Ensembl ID		ENSG00000242441	ENSG00000115297
Uniprot IDs		A0A140VKA3 Q9UNN4	O43763
PDB IDs			3A03
Enriched GO Terms of Interacting Partners?
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