GTF2A1L and NKX2-3

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		GTF2A1L	NKX2-3
Description		general transcription factor IIA subunit 1 like	NK2 homeobox 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIA Complex Cytoplasm	Chromatin Cellular_component Nucleus
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Cognition	Leukocyte Homeostasis Plasma Cell Differentiation Regulation Of Transcription By RNA Polymerase II Triglyceride Metabolic Process Biological_process Gland Morphogenesis Cell Differentiation Macrophage Differentiation Regulation Of Cell Population Proliferation Odontogenesis Of Dentin-containing Tooth CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Lymph Node Development Spleen Development Peyer's Patch Development Post-embryonic Digestive Tract Morphogenesis Leukocyte Migration
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Hepcidin/ferritin ratio ( 27846281) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Joint mobility (Beighton score) ( 27182965) Laterality in neovascular age-related macular degeneration ( 28775256) Polycystic ovary syndrome ( 21151128)	Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Colorectal cancer ( 25990418 30529582 24737748) Colorectal cancer or advanced adenoma ( 30510241) Crohn's disease ( 18587394 25489960 28067908 17554261 22412388 17554300 21102463) Dental caries ( 23064961) Granulocyte percentage of myeloid white cells ( 27863252) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hypothyroidism ( 27182965) Inflammatory bowel disease ( 28067908 23128233) Leukocyte telomere length ( 31171785) Mean corpuscular hemoglobin ( 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Pediatric autoimmune diseases ( 26301688) Red blood cell traits ( 23222517) Ulcerative colitis ( 28067908 20228798 20228799)
Interacting Genes		25 interacting genes: ASCL3 ATF4 CEBPE CSNK2A1 CSNK2A2 EMX1 EMX2 GAB1 GTF2A2 HMG20A HOXA5 HOXC11 HOXC9 ID3 MAFF MAFG NKX2-3 PAX9 RBFOX2 SIX6 SUB1 TBP TLX2 TLX3 ZBTB3	3 interacting genes: GTF2A1L SRF ZNF212
Entrez ID		11036	159296
HPRD ID		05640	05992
Ensembl ID		ENSG00000242441	ENSG00000119919
Uniprot IDs		A0A140VKA3 Q9UNN4	Q8TAU0
PDB IDs
Enriched GO Terms of Interacting Partners?
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