GNA13 and AIP

Number of citations of the paper that reports this interaction (PubMedID 19390533)
8

Data Source:
BioGRID (two hybrid)

		GNA13	AIP
Description		G protein subunit alpha 13	aryl hydrocarbon receptor interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Heterotrimeric G-protein Complex Plasma Membrane Focal Adhesion Membrane Brush Border Membrane Melanosome Extracellular Exosome	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Aryl Hydrocarbon Receptor Complex
	Molecular Function	G Protein-coupled Receptor Binding GTPase Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding GTP Binding G-protein Beta/gamma-subunit Complex Binding D5 Dopamine Receptor Binding Metal Ion Binding	Transcription Coactivator Activity Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Transcription Factor Binding Aryl Hydrocarbon Receptor Binding GAF Domain Binding Unfolded Protein Binding
	Biological Process	Signal Transduction Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Rho Protein Signal Transduction Activation Of Phospholipase D Activity Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration	Protein Peptidyl-prolyl Isomerization Protein Targeting To Mitochondrion Xenobiotic Metabolic Process Regulation Of Protein Kinase A Signaling Protein Maturation By Protein Folding Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity
Pathways		NRAGE signals death through JNK G alpha (12/13) signalling events Thromboxane signalling through TP receptor Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) CDC42 GTPase cycle RAC1 GTPase cycle	Aryl hydrocarbon receptor signalling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Periventricular white matter hyperintensities ( 32517579) White matter microstructure (global fractional anisotropy) ( 24736177)	Apolipoprotein A1 levels ( 32203549) Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Refractive error ( 32231278) Urate levels ( 31578528)
Interacting Genes		31 interacting genes: AIP AKAP3 ARHGEF1 ARHGEF11 ARHGEF12 CDH1 CDH2 CTNNB1 CXCR4 DRD5 EDNRB F2R GNA12 GPR17 MCF2 MTNR1A PPP5C PRKACA PRKCB PRKCD PRKCE PTK2B RDX RGS16 RIC8A S1PR2 S1PR3 S1PR4 TBXA2R TGFBR1 TSHR	18 interacting genes: AHR ARNT CLEC7A CSNK2A1 EGFR ERBB2 GNA13 GNAQ HSP90AA1 HTR6 IKBKG IRF7 PDE4A PPARA PTGES3 STIP1 TNNI3K TOMM20
Entrez ID		10672	9049
HPRD ID		05100	10408
Ensembl ID		ENSG00000120063	ENSG00000110711
Uniprot IDs		A0A024R8M0 Q14344	G9I2H4 O00170
PDB IDs			2LKN 4AIF 4APO
Enriched GO Terms of Interacting Partners?
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