AIP and HTR6

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		AIP	HTR6
Description		aryl hydrocarbon receptor interacting protein	5-hydroxytryptamine receptor 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Aryl Hydrocarbon Receptor Complex	Plasma Membrane Integral Component Of Plasma Membrane Cilium Dendrite Synapse
	Molecular Function	Transcription Coactivator Activity Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Transcription Factor Binding Aryl Hydrocarbon Receptor Binding GAF Domain Binding Unfolded Protein Binding	Histamine Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity
	Biological Process	Protein Peptidyl-prolyl Isomerization Protein Targeting To Mitochondrion Xenobiotic Metabolic Process Regulation Of Protein Kinase A Signaling Protein Maturation By Protein Folding Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity	G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Cerebral Cortex Cell Migration Positive Regulation Of TOR Signaling G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways		Aryl hydrocarbon receptor signalling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Serotonin receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Ziprasidone Amitriptyline Olanzapine Clozapine Loxapine Imipramine Chlorpromazine Haloperidol Amoxapine Paroxetine Cyclobenzaprine Ergoloid mesylate Doxepin Quetiapine Aripiprazole Chlorprothixene Dimethyltryptamine Lysergic acid diethylamide Iloperidone SGS518 PRX-07034 SUVN-502 Sertindole Mianserin Asenapine Zotepine Setiptiline Dihydroergocornine Gilteritinib Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Refractive error ( 32231278) Urate levels ( 31578528)	Chronotype ( 26955885 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 27494321)
Interacting Genes		18 interacting genes: AHR ARNT CLEC7A CSNK2A1 EGFR ERBB2 GNA13 GNAQ HSP90AA1 HTR6 IKBKG IRF7 PDE4A PPARA PTGES3 STIP1 TNNI3K TOMM20	32 interacting genes: ABCA2 ACTB AIP AKR1A1 AP2M1 AP4S1 ATXN10 CD160 CHN1 CMSS1 COPS5 DDRGK1 DHRS1 EIF4A3 FYN GNAQ GNAS HDGFL2 IDS MAP1B NF1 NRXN3 PARP8 RUNDC3A SCHIP1 SLC6A1 SRRT SYT5 THY1 TMEM98 TTYH1 UQCRFS1
Entrez ID		9049	3362
HPRD ID		10408	03066
Ensembl ID		ENSG00000110711	ENSG00000158748
Uniprot IDs		G9I2H4 O00170	P50406
PDB IDs		2LKN 4AIF 4APO
Enriched GO Terms of Interacting Partners?
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