TRIM3 and UBE2G2

Number of citations of the paper that reports this interaction (PubMedID 19690564)
64

Data Source:
BioGRID (two hybrid)

		TRIM3	UBE2G2
Description		tripartite motif containing 3	ubiquitin conjugating enzyme E2 G2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Early Endosome Golgi Apparatus Dendrite	Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Protein Binding Protein C-terminus Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Polyubiquitination Nervous System Development Protein Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		Interferon gamma signaling	Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Malaria ( 31844061)	Alanine aminotransferase levels ( 33547301)
Interacting Genes		34 interacting genes: ACTN4 ASL CDKN1A CEP70 CSNK1D CSNK1E DNMT1 FXR1 FXR2 KCTD7 KIF21B LNX1 LRRC8E MYO5A MYO5B ROPN1 TEAD1 TEAD2 TNFAIP3 TPTEP2-CSNK1E TRIM2 TRIM21 TSC1 UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2G2 UBE2I UBE2K UBE2U UBE2Z USP32	41 interacting genes: AMFR ARL14 AUP1 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN PSMG1 RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRAPPC10 TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4
Entrez ID		10612	7327
HPRD ID		05690	04387
Ensembl ID		ENSG00000110171	ENSG00000184787
Uniprot IDs		B7Z5Y8 O75382	P60604
PDB IDs			2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?
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