EIF3M and ZMYND10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EIF3M	ZMYND10
Description		eukaryotic translation initiation factor 3 subunit M	zinc finger MYND-type containing 10
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GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m	Cytoplasm Apical Plasma Membrane Centriolar Satellite Dynein Axonemal Particle
	Molecular Function	Translation Initiation Factor Activity Protein Binding Translation Initiation Factor Binding	Protein Binding Protein Folding Chaperone Metal Ion Binding Molecular Adaptor Activity
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Cytoplasmic Translational Initiation Translational Initiation	Cilium Movement Protein Folding Outer Dynein Arm Assembly Inner Dynein Arm Assembly Motile Cilium Assembly Protein Localization To Cilium Positive Regulation Of Motile Cilium Assembly
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Menopause (age at onset) ( 26414677) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		10 interacting genes: ABI3 APP EIF3F EXOSC10 HSPB1 METTL3 SRPK1 TRIML2 ZMYND10 ZNF783	20 interacting genes: ACTR3 CDR1 CLK1 CYSRT1 EIF3M IFT43 KRTAP10-3 MTUS2 NR0B2 NUTM1 NUTM2F RALGDS RBM11 RNF181 SERINC1 SNX11 TBX5 TCF4 TSC22D4 WBP1
Entrez ID		10480	51364
HPRD ID		09969	06145
Ensembl ID		ENSG00000149100	ENSG00000004838
Uniprot IDs		Q7L2H7	O75800
PDB IDs		3J8B 3J8C 6FEC 6YBD 6ZMW 6ZON 6ZP4 6ZVJ 7A09	2D8Q 2DAN
Enriched GO Terms of Interacting Partners?
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