EIF3M and ZNF783

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EIF3M	ZNF783
Description		eukaryotic translation initiation factor 3 subunit M	zinc finger protein 783
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m	Nucleus
	Molecular Function	Translation Initiation Factor Activity Protein Binding Translation Initiation Factor Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Cytoplasmic Translational Initiation Translational Initiation	Regulation Of Transcription By RNA Polymerase II
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Menopause (age at onset) ( 26414677) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)	Birth weight ( 31043758) Heel bone mineral density ( 30598549)
Interacting Genes		10 interacting genes: ABI3 APP EIF3F EXOSC10 HSPB1 METTL3 SRPK1 TRIML2 ZMYND10 ZNF783	4 interacting genes: EIF3M PIN1 ZNF212 ZNF398
Entrez ID		10480	100289678
HPRD ID		09969
Ensembl ID		ENSG00000149100	ENSG00000204946
Uniprot IDs		Q7L2H7	Q6ZMS7
PDB IDs		3J8B 3J8C 6FEC 6YBD 6ZMW 6ZON 6ZP4 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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