FAM3C and AHNAK2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FAM3C	AHNAK2
Description		FAM3 metabolism regulating signaling molecule C	AHNAK nucleoprotein 2
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Platelet Dense Granule Lumen Extracellular Exosome	Nucleus Cytoplasm Cytosol Plasma Membrane T-tubule Sarcolemma
	Molecular Function	Cytokine Activity Protein Binding	Protein Binding
	Biological Process	Signal Transduction Biological_process Negative Regulation Of Gluconeogenesis	Regulation Of RNA Splicing
Pathways		Platelet degranulation
Drugs
Diseases
GWAS		Biomedical quantitative traits ( 19396169) Bone mineral density (paediatric, lower limb) ( 24945404) Bone mineral density (paediatric, skull) ( 24945404) Bone mineral density (paediatric, total body less head) ( 24945404) Bone mineral density (paediatric, upper limb) ( 24945404) Calcaneus stiffness index ( 30779856) Forearm bone mineral density ( 26367794) Hand grip strength ( 27325353) Heel bone mineral density ( 30598549 28869591) Lung adenocarcinoma ( 28604730) Pediatric bone mineral content (radius) ( 26041818) Phenylephrine infusion rate during anesthesia ( 31455332) Total body bone mineral density ( 30172743) Ulna and radius bone mineral density ( 30172743)	Cerebrospinal fluid t-tau levels ( 29274321) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 33272962 26663301)
Interacting Genes		48 interacting genes: AHNAK2 BIK BNIP2 CLEC17A CLEC2D CLEC4E CREB3 CREB3L1 CXADR CYB5R3 ELOVL4 ERGIC3 EVI2B FAM209A FCGR1A FCGRT FFAR2 FKBP7 GGT6 GJB5 GPR42 GPX8 HHLA2 KCNA2 KIR2DL3 LMNA LRRC25 MFF PDZK1IP1 RELL2 RMDN3 RNASEH1 SAR1A SCN3B SLC10A6 SLC16A2 SLC18A1 SLC35C2 SPINT1 SSMEM1 STX1A TEX29 TMEM248 TMEM45B TMEM71 TMEM80 TMPRSS2 TMX2	18 interacting genes: ABLIM2 ASGR1 C3orf52 COA8 CTSA CYB5B CYBC1 FAM3C GABARAPL1 GABARAPL2 IGFBP5 PRAP1 SUMO2 TRMT61A TSPO2 UBIAD1 VAMP3 ZFPL1
Entrez ID		10447	113146
HPRD ID		12270	12261
Ensembl ID		ENSG00000196937	ENSG00000185567
Uniprot IDs		Q92520	Q8IVF2
PDB IDs		5LC2	4CN0
Enriched GO Terms of Interacting Partners?
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