GNE and WWOX

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

GNE

WWOX

Description glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase WW domain containing oxidoreductase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder (inflammation and infection response interaction) ( 25781172)
  • Bisphosphonate-associated atypical femoral fracture ( 31006051)
  • Acute graft versus host disease in bone marrow transplantation (recipient effect) ( 27595289)
  • Age at first sexual intercourse ( 34211149)
  • Alzheimer's disease (late onset) ( 30820047)
  • Anorexia nervosa ( 23568457)
  • Bipolar disorder (body mass index interaction) ( 24322204)
  • Brain morphology (MOSTest) ( 32665545)
  • Brain volume in infants (white matter) ( 28763065)
  • Cardiac structure and function ( 19584346)
  • Clozapine-induced cytotoxicity ( 25656473)
  • Colorectal cancer ( 30529582 29228715)
  • Daytime sleep phenotypes ( 27126917)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Early-onset Parkinson's disease ( 28256260)
  • Eosinophil counts ( 32888494)
  • Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678)
  • Familial squamous cell lung carcinoma ( 29924316)
  • FEV1 ( 30804560)
  • ghrelin levels ( 33852427)
  • Gut microbiota relative abundance (Faecalibacterium) ( 33208821)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Hip shape (DXA scan) ( 30320955)
  • Idiopathic dilated cardiomyopathy ( 29495422)
  • Lung function (forced vital capacity) ( 24929828)
  • Lung function (FVC) ( 30804560)
  • Lymphocyte counts ( 32888494)
  • Macular thickness ( 30535121)
  • Major depressive disorder x sex interaction ( 34099189)
  • Metabolite levels ( 23823483)
  • Metabolite levels (5-HIAA) ( 23319000)
  • Molybdenum levels ( 26025379)
  • Multiple sclerosis ( 31604244 24076602)
  • Obesity ( 21552555)
  • Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
  • Parkinson's disease progression (cognitive) ( 33958783)
  • Peak expiratory flow ( 30804560)
  • Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954)
  • Platelet count ( 32888494)
  • Plateletcrit ( 32888494)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Pulmonary function ( 21946350)
  • Pulmonary function (smoking interaction) ( 23284291)
  • Radiation response ( 20923822)
  • Red blood cell count ( 32888494)
  • Refractive error ( 32231278)
  • Response to amphetamines ( 22952603)
  • Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309)
  • Response to fenofibrate (HDL cholesterol levels) ( 27002377)
  • Serum thyroid-stimulating hormone levels ( 25436638)
  • Serum uric acid levels in response to allopurinol in gout ( 25676789)
  • Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770)
  • Systemic juvenile idiopathic arthritis ( 27927641)
  • Triglyceride levels ( 34074324)
  • Type 2 diabetes ( 22158537)
  • Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes 66 interacting genes: ADAMTSL4 C22orf39 CFP CRMP1 CYSRT1 ECM1 EGFL7 GRN GTPBP3 HOXA1 KIAA1549 KPRP KRT31 KRT34 KRT40 KRT83 KRT85 KRT86 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP13-2 KRTAP13-3 KRTAP17-1 KRTAP19-2 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-4 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 MDFI MGAT5B NBPF19 NID2 NOTCH2NLA PLA2G10 PRICKLE4 RIF1 SIGMAR1 SPRY1 SPRY2 SPRY3 SSC4D TRIM27 TRIM42 TRIP6 TSPAN4 VWC2 WDR83 WWOX ZBTB16 116 interacting genes: ABHD11 ABI2 ACAT2 ACY1 ADRA2C ANAPC11 ANXA11 APBB2 ARRDC3 C10orf55 C11orf87 C19orf54 CCDC24 CEACAM6 CLNK CNNM3 CPSF2 CPSF6 CPSF7 CREB5 CSNK2B CTAG1A CTAG1B CTDSP1 DAZAP2 DMRT3 ENKD1 ERBB4 EZR FAM214B FAM222B FEM1A FIP1L1 FOXD4L1 FOXI1 FRS3 GCM2 GEM GLIS2 GNE HNRNPK HOXA1 HOXC8 HSPB2 HSPB2-C11orf52 HYAL2 IFIT2 INCA1 KLHDC7B KLHL38 KRT3 KRT34 KRT75 KRTAP11-1 LASP1 LATS1 LITAF LMO3 MAPK8 MED25 MKRN3 MYG1 MYOZ1 MYOZ2 NEDD9 NUDT21 OLIG3 OTX1 PATL1 PATZ1 PAX9 PBX4 PEF1 PITX2 PLAC8 PLEKHN1 PLSCR3 PPP1R32 PSMB8 RAMAC RUSC1 SAXO1 SCAMP3 SEC23IP SF3B3 SH2D4A SHC3 SLC15A2 SMAD4 SMR3A SNRPC SRC TCERG1 TCHP TEKT3 TEX37 TFAP2C TFG TNK2 TP53 TP73 TRIM69 TSGA10IP UBB UFSP1 VENTX VEZF1 VPS37C WDR33 WIPF2 YPEL3 ZBTB32 ZIC1 ZNF135 ZNF414 ZNF581
Entrez ID 10020 51741
HPRD ID 04825 05501
Ensembl ID ENSG00000159921 ENSG00000186153
Uniprot IDs Q9Y223 A0A411HBC7 Q9NZC7
PDB IDs 2YHW 2YHY 2YI1 3EO3 4ZHT 1WMV
Enriched GO Terms of Interacting Partners?
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