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TNFRSF18

Description TNF receptor superfamily member 18
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • External Side Of Plasma Membrane
Molecular Function
  • Tumor Necrosis Factor-activated Receptor Activity
  • Protein Binding
Biological Process
  • Positive Regulation Of Leukocyte Migration
  • Apoptotic Process
  • Signal Transduction
  • Tumor Necrosis Factor-mediated Signaling Pathway
  • Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
  • Negative Regulation Of Apoptotic Process
  • Positive Regulation Of Cell Adhesion
Pathways
  • TNFs bind their physiological receptors
  • RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
Drugs
Diseases
GWAS
  • Inflammatory bowel disease ( 23128233)
Interacting Genes 13 interacting genes: AKR1C1 ARHGEF16 BTK DZIP3 KCNAB2 LGALS8 LNX1 TNFSF18 TRAF1 TRAF2 TRAF3 UBQLN2 WRAP73
Entrez ID 8784
HPRD ID 04879
Ensembl ID ENSG00000186891
Uniprot IDs A0A0R7FDM1 Q9Y5U5
PDB IDs 7KHD
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025