NR1D2 and NCOA5

Number of citations of the paper that reports this interaction (PubMedID 11113208)
25

Data Source:
HPRD (in vitro, two hybrid)

		NR1D2	NCOA5
Description		nuclear receptor subfamily 1 group D member 2	nuclear receptor coactivator 5
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex	Extracellular Space Nucleoplasm Actin Cytoskeleton
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Nuclear Receptor Transcription Coactivator Activity Signaling Receptor Activity Transcription Factor Activity, Direct Ligand Regulated Sequence-specific DNA Binding	Chromatin Binding RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Multicellular Organism Development Hormone-mediated Signaling Pathway Regulation Of Lipid Metabolic Process Cell Differentiation Intracellular Receptor Signaling Pathway Response To Lipid Regulation Of Circadian Rhythm Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Circadian Behavior Regulation Of Inflammatory Response Negative Regulation Of Inflammatory Response Lipid Homeostasis Energy Homeostasis Regulation Of Skeletal Muscle Cell Differentiation	Glucose Homeostasis Negative Regulation Of Insulin Receptor Signaling Pathway
Pathways		Nuclear Receptor transcription pathway
Drugs			(16ALPHA,17ALPHA)-ESTRA-1,3,5(10)-TRIENE-3,16,17-TRIOL
Diseases
GWAS		Acne (severe) ( 24927181) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Asthma ( 29273806) Cognitive ability ( 29186694) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483)	Crohn's disease ( 28067908) Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831) Follicular lymphoma or multiple sclerosis ( 31407831) Hodgkin's lymphoma ( 30194254) Inflammatory bowel disease ( 28067908) Marginal zone lymphoma or multiple sclerosis ( 31407831) Multiple sclerosis ( 31604244 21833088) Systemic lupus erythematosus ( 28714469) Tonsillectomy ( 27182965 28928442)
Interacting Genes		24 interacting genes: CRY1 CSNK1E CSNK2A2 CUL1 DELEC1 GTF2B HDAC1 KRT40 KRTAP10-9 KRTAP4-2 MID2 NCOA5 NCOR1 NOTCH2NLA NR1D1 PRMT6 RBPMS RGN RORC SIN3B TAF6 TAF9 TRIM27 UBE2I	8 interacting genes: CDC37 HTATIP2 KHDRBS2 KHDRBS3 NR1D2 NTAQ1 SYT16 TSC22D1
Entrez ID		9975	57727
HPRD ID		03809	14813
Ensembl ID		ENSG00000174738	ENSG00000124160
Uniprot IDs		B4DXD3 F1D8P2 Q14995	Q9HCD5
PDB IDs		2V0V 2V7C 3CQV 4N73	1V95 2J7X 2J7Y 4ZI1
Enriched GO Terms of Interacting Partners?
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