NR1D2 and SIN3B

Number of citations of the paper that reports this interaction (PubMedID 9611234)
31

Data Source:
BioGRID (pull down)

		NR1D2	SIN3B
Description		nuclear receptor subfamily 1 group D member 2	SIN3 transcription regulator family member B
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex	Histone Deacetylase Complex Chromatin X Chromosome Y Chromosome XY Body Nucleus Nucleoplasm Cytoplasm Sin3 Complex Autosome
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Nuclear Receptor Transcription Coactivator Activity Signaling Receptor Activity Transcription Factor Activity, Direct Ligand Regulated Sequence-specific DNA Binding	Chromatin Binding Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Multicellular Organism Development Hormone-mediated Signaling Pathway Regulation Of Lipid Metabolic Process Cell Differentiation Intracellular Receptor Signaling Pathway Response To Lipid Regulation Of Circadian Rhythm Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Circadian Behavior Regulation Of Inflammatory Response Negative Regulation Of Inflammatory Response Lipid Homeostasis Energy Homeostasis Regulation Of Skeletal Muscle Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Histone Deacetylation Regulation Of Lipid Metabolic Process
Pathways		Nuclear Receptor transcription pathway	NoRC negatively regulates rRNA expression RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Asthma ( 29273806) Cognitive ability ( 29186694) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483)
Interacting Genes		24 interacting genes: CRY1 CSNK1E CSNK2A2 CUL1 DELEC1 GTF2B HDAC1 KRT40 KRTAP10-9 KRTAP4-2 MID2 NCOA5 NCOR1 NOTCH2NLA NR1D1 PRMT6 RBPMS RGN RORC SIN3B TAF6 TAF9 TRIM27 UBE2I	22 interacting genes: AURKA COPS2 GDF15 H3-4 HDAC1 HDAC9 IKZF1 IKZF4 MAD1L1 MXD1 MXI1 NR1D2 POR REST RNF220 SETDB1 SMARCA2 SMARCA4 SMARCB1 SMARCE1 TP53 ZBTB16
Entrez ID		9975	23309
HPRD ID		03809	09691
Ensembl ID		ENSG00000174738	ENSG00000127511
Uniprot IDs		B4DXD3 F1D8P2 Q14995	B7Z392 M0QYC5 O75182
PDB IDs		2V0V 2V7C 3CQV 4N73
Enriched GO Terms of Interacting Partners?
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