NCOA5 and NR1D2

Number of citations of the paper that reports this interaction (PubMedID 11113208)
25

Data Source:
HPRD (in vitro, two hybrid)

		NCOA5	NR1D2
Description		nuclear receptor coactivator 5	nuclear receptor subfamily 1 group D member 2
Image
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Actin Cytoskeleton	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex
	Molecular Function	Chromatin Binding RNA Binding Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Nuclear Receptor Transcription Coactivator Activity Signaling Receptor Activity Transcription Factor Activity, Direct Ligand Regulated Sequence-specific DNA Binding
	Biological Process	Glucose Homeostasis Negative Regulation Of Insulin Receptor Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Multicellular Organism Development Hormone-mediated Signaling Pathway Regulation Of Lipid Metabolic Process Cell Differentiation Intracellular Receptor Signaling Pathway Response To Lipid Regulation Of Circadian Rhythm Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Circadian Behavior Regulation Of Inflammatory Response Negative Regulation Of Inflammatory Response Lipid Homeostasis Energy Homeostasis Regulation Of Skeletal Muscle Cell Differentiation
Pathways			Nuclear Receptor transcription pathway
Drugs		(16ALPHA,17ALPHA)-ESTRA-1,3,5(10)-TRIENE-3,16,17-TRIOL
Diseases
GWAS		Crohn's disease ( 28067908) Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831) Follicular lymphoma or multiple sclerosis ( 31407831) Hodgkin's lymphoma ( 30194254) Inflammatory bowel disease ( 28067908) Marginal zone lymphoma or multiple sclerosis ( 31407831) Multiple sclerosis ( 31604244 21833088) Systemic lupus erythematosus ( 28714469) Tonsillectomy ( 27182965 28928442)	Acne (severe) ( 24927181) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Asthma ( 29273806) Cognitive ability ( 29186694) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: CDC37 HTATIP2 KHDRBS2 KHDRBS3 NR1D2 NTAQ1 SYT16 TSC22D1	24 interacting genes: CRY1 CSNK1E CSNK2A2 CUL1 DELEC1 GTF2B HDAC1 KRT40 KRTAP10-9 KRTAP4-2 MID2 NCOA5 NCOR1 NOTCH2NLA NR1D1 PRMT6 RBPMS RGN RORC SIN3B TAF6 TAF9 TRIM27 UBE2I
Entrez ID		57727	9975
HPRD ID		14813	03809
Ensembl ID		ENSG00000124160	ENSG00000174738
Uniprot IDs		Q9HCD5	B4DXD3 F1D8P2 Q14995
PDB IDs		1V95 2J7X 2J7Y 4ZI1	2V0V 2V7C 3CQV 4N73
Enriched GO Terms of Interacting Partners?
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