SIN3B and MXI1

Number of citations of the paper that reports this interaction (PubMedID 15467743)
6

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		SIN3B	MXI1
Description		SIN3 transcription regulator family member B	MAX interactor 1, dimerization protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin X Chromosome Y Chromosome XY Body Nucleus Nucleoplasm Cytoplasm Sin3 Complex Autosome	Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol RNA Polymerase II Transcription Factor Complex
	Molecular Function	Chromatin Binding Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Transcription Corepressor Activity Protein Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Histone Deacetylation Regulation Of Lipid Metabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Proliferation Cytoplasmic Sequestering Of Transcription Factor
Pathways		NoRC negatively regulates rRNA expression RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS			Birth weight ( 31043758) Diastolic blood pressure ( 30224653) Neutrophil count ( 29403010) Normalized brain volume ( 19010793) Platelet count ( 29403010) White blood cell count ( 29403010)
Interacting Genes		22 interacting genes: AURKA COPS2 GDF15 H3-4 HDAC1 HDAC9 IKZF1 IKZF4 MAD1L1 MXD1 MXI1 NR1D2 POR REST RNF220 SETDB1 SMARCA2 SMARCA4 SMARCB1 SMARCE1 TP53 ZBTB16	18 interacting genes: APP CALCOCO2 ENTPD5 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 MAX MYC NOTCH2NLA RPL23AP32 SIN3A SIN3B SMARCB1 SMC3 USHBP1
Entrez ID		23309	4601
HPRD ID		09691	02486
Ensembl ID		ENSG00000127511	ENSG00000119950
Uniprot IDs		B7Z392 M0QYC5 O75182	A0A0S2Z3X5 P50539
PDB IDs
Enriched GO Terms of Interacting Partners?
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