TMCC2 and ZNF587

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TMCC2	ZNF587
Description		transmembrane and coiled-coil domain family 2	zinc finger protein 587
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Integral Component Of Membrane	Nucleus
	Molecular Function	Protein Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Amyloid Precursor Protein Metabolic Process	Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular hemoglobin concentration ( 27863252) Mean corpuscular volume ( 27863252) Mean platelet volume ( 22139419 24026423 19820697 27863252) Platelet count ( 22139419) Platelet distribution width ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
Interacting Genes		29 interacting genes: AKT1 AMOTL2 APP CCDC33 CDR2 CFAP206 DIP2A DPY30 EIF4E2 FAM161A FAM74A4 FAM90A1 FBF1 HGS HNRNPLL HSPD1 IQUB KAT5 PRPF31 PTOV1 RHOXF2 TLE5 UBA1 WT1-AS ZNF250 ZNF417 ZNF581 ZNF587 ZNF688	43 interacting genes: ADAMTSL4 CARD9 CCDC136 CEP44 CEP70 CSRNP1 FSD2 GOLGA2 GOPC HMBOX1 KRT38 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-4 KRTAP5-9 MDFI MEOX2 MID2 MTUS2 NOTCH2NLA PLSCR1 PNMA2 PRPF31 RUNDC3A SMAD9 SPRY2 SSX2IP STX11 TCF4 TMCC2 TNS2 TRAF1 TRIM36 TRIM41 TRIM54 TSGA10 ZBTB8A ZNF417
Entrez ID		9911	84914
HPRD ID		11040	15864
Ensembl ID		ENSG00000133069	ENSG00000198466
Uniprot IDs		A0A0C4DFR1 O75069 Q8IW47	Q96SQ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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